{"id":"W2327116552","doi":"10.1002/wnan.1406","title":"Modifying the tumor microenvironment using nanoparticle therapeutics","year":2016,"lang":"en","type":"review","venue":"Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Institutes of Health; Ontario Institute for Cancer Research; National Cancer Institute; Prostate Cancer Foundation","keywords":"Stromal cell; Nanomedicine; Cancer; Tumor microenvironment; Stroma; Cancer research; Medicine; Disease; Tumor cells; Bioinformatics; Internal medicine; Nanotechnology; Biology; Nanoparticle; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003179022,0.0007929467,0.0008157483,0.001272977,0.0002438896,0.0006925025,0.0005405541,0.001094655,0.001117865],"category_scores_gemma":[0.0002758577,0.0002578195,0.0004171634,0.0007449396,0.0004774454,0.0009573596,0.0005610936,0.001252782,0.001243383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004934944,"about_ca_system_score_gemma":0.0004301727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005432612,"about_ca_topic_score_gemma":0.0007966441,"domain_scores_codex":[0.9998566,0.00002143154,0.00001049476,0.00003216242,0.0000598178,0.00001946256],"domain_scores_gemma":[0.9999199,0.00003442378,0.00001302051,0.00000401941,0.00002020262,0.000008530736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000530042,0.0001283287,0.0001646077,0.008937349,0.00006005854,0.0003569628,0.00009930917,0.0009476698,0.05388419,0.00896237,0.01610999,0.9102961],"study_design_scores_gemma":[0.00001427456,0.000201957,0.000524513,0.001262475,0.00007426751,0.001961961,0.00005254846,0.0006246998,0.02907747,0.002835635,0.9633414,0.00002883232],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007905182,0.9952316,0.001178005,0.0002986826,0.0002741318,0.000009068717,0.00001050386,0.00002535654,0.002182185],"genre_scores_gemma":[0.006656858,0.9898313,0.0009149854,0.0002601037,0.0001739374,0.00001983825,0.00002560671,0.000006198858,0.002111244],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001272977,"threshold_uncertainty_score":0.003739595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08465625956925253,"score_gpt":0.3772480571232134,"score_spread":0.2925917975539609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}