{"id":"W2327142228","doi":"10.1097/tp.0000000000001154","title":"Quantification of Alloantibody-Mediated Cytotoxicity In Vivo","year":2016,"lang":"en","type":"article","venue":"Transplantation","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Allorecognition; Cytotoxicity; Immunology; Priming (agriculture); Major histocompatibility complex; Antibody; Biology; Antigen; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002259888,0.0000911373,0.0001885814,0.0002223556,0.0000156726,0.000002827403,0.00004616788,0.00007767069,0.0002916571],"category_scores_gemma":[0.0000409644,0.00006521107,0.00005283223,0.0002313635,0.00005461285,0.0001298093,0.00000113761,0.00005198137,0.0000522812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003010785,"about_ca_system_score_gemma":0.000065176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006322667,"about_ca_topic_score_gemma":0.0000576152,"domain_scores_codex":[0.9990684,0.0000764189,0.0003736628,0.0001562948,0.0001925636,0.0001326012],"domain_scores_gemma":[0.9994634,0.000202954,0.00008325462,0.0001398594,0.00006427962,0.00004624025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002458995,0.0001253195,0.02964717,0.0001897263,0.00001442598,0.00002125689,0.0004907292,0.000004103539,0.9658576,0.0004195607,0.00001746622,0.000753605],"study_design_scores_gemma":[0.002934774,0.00009653545,0.3924873,0.0002911983,0.00003633469,0.00003631686,0.00002505371,0.00006745519,0.6038461,0.00002004423,0.00009423035,0.00006464217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819444,0.00003832023,0.01600142,0.0005986771,0.00004695018,0.0003027464,0.0001010763,0.00004441268,0.0009219291],"genre_scores_gemma":[0.9979389,0.001295091,0.0002950304,0.00006818344,0.00001043492,0.00001189004,0.00009186737,0.0000116712,0.0002769842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3628401,"threshold_uncertainty_score":0.319344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02064760632261291,"score_gpt":0.2881714178711723,"score_spread":0.2675238115485594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}