{"id":"W2327149980","doi":"10.1101/pdb.prot088807","title":"Synthetic Genetic Array Analysis","year":2016,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Genetics; Mutant; Computational biology; Biology; Gene; Genetic analysis; Allele; Mutation; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002393502,0.0001786024,0.0001953228,0.0001258065,0.00008689009,0.00005166155,0.0004135228,0.0001252981,0.0001428047],"category_scores_gemma":[0.0001342255,0.0001290025,0.0001955417,0.000293718,0.0001018123,0.000002972385,0.0001471116,0.00006974511,0.0001503025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002550856,"about_ca_system_score_gemma":0.0001022662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009315302,"about_ca_topic_score_gemma":0.00001275791,"domain_scores_codex":[0.9984384,0.00008338648,0.000240291,0.0005392366,0.0002686727,0.0004299844],"domain_scores_gemma":[0.9987793,0.00002132177,0.00006811269,0.0008211346,0.0001233323,0.0001868033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005659124,0.00005598981,0.02200362,0.00002373243,0.0001829204,0.00000452227,0.000002251928,0.0000303106,0.9765113,0.0002102032,0.0001071823,0.0008113562],"study_design_scores_gemma":[0.000443668,0.0002087753,0.0293121,0.00004398832,0.0000453302,5.453405e-7,0.000001018073,0.00002242641,0.8706091,0.00001294775,0.09908248,0.0002176308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8937274,0.0005565714,0.06400823,0.0005839812,0.000107898,0.03911411,0.00005709871,0.0000985073,0.0017462],"genre_scores_gemma":[0.9670247,0.00003405373,0.002054096,0.00006197957,0.0002158994,0.02918991,7.473477e-7,0.00003627844,0.001382289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1059022,"threshold_uncertainty_score":0.5260569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01640254900568938,"score_gpt":0.287443695608684,"score_spread":0.2710411466029946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}