{"id":"W23274571","doi":"10.1200/jco.2009.27.15_suppl.3527","title":"Hypertension (HTN) in National Cancer Institute of Canada Clinical Trials Group study BR.24: A randomized, double-blind phase II trial of carboplatin (C) and paclitaxel (P) with either daily oral cediranib (CED), an inhibitor of vascular endothelial growth factor receptors, or placebo, in patients with advanced non-small cell lung cancer","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Medicine; Internal medicine; Hazard ratio; Placebo; Proportional hazards model; Adverse effect; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003604283,0.001135504,0.00197744,0.0003697223,0.0007312396,0.0009554938,0.0008450972,0.0009309328,0.003367584],"category_scores_gemma":[0.002567964,0.0005885925,0.001231259,0.000747177,0.0007814636,0.0003218542,0.0003566252,0.001939591,0.000382526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002996186,"about_ca_system_score_gemma":0.008553477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.08358345,"about_ca_topic_score_gemma":0.2473324,"domain_scores_codex":[0.9984914,0.0009815783,0.00006404638,0.0001289083,0.0001911419,0.000142902],"domain_scores_gemma":[0.9984787,0.0002136388,0.0003552834,0.00008262732,0.0001516582,0.000718098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9367876,0.006773464,0.01062464,0.001430921,0.003116336,0.0001594776,0.0001272439,0.0008270653,0.004478737,0.0002221483,0.009381751,0.02607045],"study_design_scores_gemma":[0.9343634,0.02732392,0.03148706,0.00009930454,0.001690346,0.00009503688,0.00002774158,0.0005730402,0.0005353879,0.0001075851,0.003659525,0.00003762567],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9520577,0.01358662,0.0006341164,0.001906972,0.0003926148,0.0123296,0.01383385,0.000133379,0.005125206],"genre_scores_gemma":[0.9536882,0.007434938,0.003725813,0.002776182,0.0005061575,0.01337431,0.01015452,0.00004544975,0.008294486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08358345,"threshold_uncertainty_score":0.1661938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1025637392017717,"score_gpt":0.4613624168579121,"score_spread":0.3587986776561403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}