{"id":"W2327475399","doi":"10.1038/mtna.2016.14","title":"A Novel p19 Fusion Protein as a Delivery Agent for Short-interfering RNAs","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Small interfering RNA; RNA interference; Gene knockdown; Cytoplasm; Cell biology; Transactivation; Biology; Fusion protein; RNA; Molecular biology; Chemistry; Transcription factor; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009717265,0.0004784078,0.0002515204,0.0002061178,0.0003476368,0.0002286154,0.0003427156,0.0005485977,0.001240904],"category_scores_gemma":[0.0000802194,0.0001424713,0.0003102834,0.0002016611,0.0002072767,0.0003821334,0.0002624537,0.0004821941,0.00087618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003877185,"about_ca_system_score_gemma":0.0002647116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005481082,"about_ca_topic_score_gemma":0.000441144,"domain_scores_codex":[0.9998851,0.00001428806,0.000007764179,0.00003244486,0.00004117781,0.00001934749],"domain_scores_gemma":[0.999962,0.000006093062,0.00001196234,0.000002491233,0.000005918063,0.0000116102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003455894,0.00002064528,0.00008607985,0.0000491036,0.000004817146,0.0001786241,0.00001256046,0.00007756076,0.9960607,0.0003389628,0.0001710031,0.002965384],"study_design_scores_gemma":[0.00002253273,0.0003267562,0.0009724081,0.000006664704,0.00002323924,0.001400132,0.00001367785,0.001539687,0.9723949,0.0001054971,0.02318323,0.00001129912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8483316,0.01091208,0.1253208,0.0009065699,0.0003460083,0.000397941,0.0009437094,0.001054723,0.01178658],"genre_scores_gemma":[0.9204766,0.00493587,0.05675804,0.0002716426,0.00007738064,0.0002683425,0.002045922,0.0001053069,0.01506091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001240904,"threshold_uncertainty_score":0.004151225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01817192176480569,"score_gpt":0.2553642448611577,"score_spread":0.237192323096352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}