{"id":"W2327510296","doi":"10.1021/ab500127y","title":"High-Resolution Visualization of the Osteocyte Lacuno-Canalicular Network Juxtaposed to the Surface of Nanotextured Titanium Implants in Human","year":2015,"lang":"en","type":"article","venue":"ACS Biomaterials Science & Engineering","topic":"Bone Tissue Engineering Materials","field":"Engineering","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Vetenskapsrådet; IngaBritt och Arne Lundbergs Forskningsstiftelse; Stiftelsen Handlanden Hjalmar Svenssons; Ontario Trillium Foundation; Västra Götalandsregionen","keywords":"Osteocyte; Bone canaliculus; Osseointegration; Materials science; Nanotopography; Mechanotransduction; Biomedical engineering; Titanium; Nanotechnology; Electron tomography; Implant; Chemistry; Transmission electron microscopy; Osteoblast; Scanning transmission electron microscopy; Anatomy; Cell biology; Metallurgy; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001596166,0.0002328213,0.0003781771,0.0001561822,0.00007011273,0.00007349301,0.0007328265,0.00009399059,0.000007545152],"category_scores_gemma":[0.0001357906,0.0001732199,0.00003755761,0.001449547,0.00008901653,0.0002305594,0.0001828141,0.00004249412,0.000007188901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001909579,"about_ca_system_score_gemma":0.00005449023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003207871,"about_ca_topic_score_gemma":0.00005010045,"domain_scores_codex":[0.9981174,0.00005463358,0.0006089955,0.0002297773,0.0004951276,0.0004940891],"domain_scores_gemma":[0.9991265,0.00002954936,0.000114156,0.0005232545,0.0001064249,0.0001001241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000003699009,0.000003488795,0.00003856382,0.00002301449,0.000005139573,6.780114e-7,0.0002021109,0.4755756,0.5234219,0.0006445138,0.00007568658,0.000005598509],"study_design_scores_gemma":[0.0002423043,0.00003357558,0.007144131,0.0001591766,0.00001280167,0.000007331532,0.00002044601,0.009534247,0.982354,0.00002303856,0.0002769493,0.0001920307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927926,0.0001583785,0.003771781,0.00003748162,0.002613505,0.0004316295,0.00003119159,0.0001488064,0.00001461834],"genre_scores_gemma":[0.9984952,0.000005015754,0.001289069,0.00000739335,0.0001308038,0.00001481725,0.000007880501,0.00004311925,0.000006725325],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4660414,"threshold_uncertainty_score":0.7063703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01329784483353837,"score_gpt":0.2347288761225167,"score_spread":0.2214310312889784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}