{"id":"W2327515279","doi":"10.1017/cjn.2014.54","title":"The effect of intra-arterial delivery of temozolomide with or without osmotic blood-brain barrier disruption and combined to radiotherapy","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Temozolomide; Blood–brain barrier; Radiation therapy; Medicine; Anesthesia; Internal medicine; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008470298,0.0003733013,0.0003377622,0.0002497502,0.00009499711,0.0002311161,0.0001810372,0.0002435505,0.001469485],"category_scores_gemma":[0.00009072183,0.0001108887,0.000229512,0.0001936276,0.0003121783,0.0001878133,0.0001177575,0.0005883746,0.0001629359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002639584,"about_ca_system_score_gemma":0.0004534923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001750636,"about_ca_topic_score_gemma":0.002913088,"domain_scores_codex":[0.9999404,0.0000113602,0.000003125348,0.00001314892,0.000009966456,0.00002203106],"domain_scores_gemma":[0.9999552,0.0000065007,0.00001157183,0.00000519985,0.00000407911,0.00001750893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004672446,0.000648013,0.0003114857,0.0002274898,0.00007547852,0.0001130162,0.00004776605,0.0003341662,0.9764613,0.0004241724,0.0005158267,0.01616892],"study_design_scores_gemma":[0.0004490865,0.01052647,0.004750642,0.00001271643,0.0001809875,0.0003731945,0.00004246316,0.001309639,0.9768182,0.00008439792,0.005440862,0.00001130942],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951296,0.001776081,0.00122883,0.0001048855,0.00006506146,0.00004896291,0.0002109212,0.0001082363,0.001327478],"genre_scores_gemma":[0.9950399,0.001228203,0.001336093,0.00004123788,0.00001733584,0.00004187474,0.0002104266,0.00001473611,0.002070251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001750636,"threshold_uncertainty_score":0.004915953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01291920966071115,"score_gpt":0.2601953173522111,"score_spread":0.2472761076914999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}