{"id":"W2327657961","doi":"10.1021/jo3010606","title":"Tandem Ring-Opening Decarboxylation of Cyclopropane Hemimalonates with Sodium Azide: A Short Route to γ-Aminobutyric Acid Esters","year":2012,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Cyclopropane; Decarboxylation; Chemistry; Sodium azide; Tandem; Azide; Ring (chemistry); Adduct; Sodium; Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000180209,0.000557074,0.0002799069,0.0002121611,0.0001953041,0.0001574415,0.0003827054,0.0003215687,0.001716148],"category_scores_gemma":[0.0001616353,0.0002069366,0.0002272461,0.0002659076,0.0001803424,0.0004434693,0.0003555349,0.0005982564,0.0007395888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002508254,"about_ca_system_score_gemma":0.0003531648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003628712,"about_ca_topic_score_gemma":0.001028124,"domain_scores_codex":[0.9998626,0.00001766155,0.00001273427,0.00002705467,0.00002754474,0.00005246331],"domain_scores_gemma":[0.9999186,0.00001224972,0.00002051323,0.00001196581,0.00001437984,0.00002227446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00017913,0.0000341084,0.0001516755,0.000124043,0.00002269058,0.0002366272,0.0000594603,0.0002406967,0.9916921,0.0007019428,0.0001328549,0.006424665],"study_design_scores_gemma":[0.000009240252,0.0001507866,0.0002748529,0.000004219034,0.00000689257,0.000140008,0.00001302663,0.0001842911,0.9974499,0.00005053306,0.001710616,0.000005648551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9612215,0.003786654,0.02261587,0.000230118,0.0001722919,0.0001527869,0.0004481254,0.0002246546,0.01114798],"genre_scores_gemma":[0.9870667,0.002087685,0.006627689,0.00004854507,0.00001516057,0.0000514691,0.0002258425,0.00002646215,0.00385039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001716148,"threshold_uncertainty_score":0.00574106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0114708864186066,"score_gpt":0.2263341491080563,"score_spread":0.2148632626894497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}