{"id":"W2327793129","doi":"10.5692/clinicalneurol.49.838","title":"Pre-symptomatic detection of Alzheimer's disease and mild cognitive impairment","year":2009,"lang":"en","type":"review","venue":"Rinsho Shinkeigaku","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"","keywords":"Neuroimaging; Biomarker; Cognitive impairment; Disease; Positron emission tomography; Medicine; Cognitive decline; Dementia; Cognition; Alzheimer's disease; Neuroscience; Psychology; Internal medicine; Psychiatry; Radiology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001967824,0.0006667832,0.00198865,0.0004085793,0.0001229645,0.00003856612,0.0001234077,0.0002550839,0.00007692891],"category_scores_gemma":[0.00009289696,0.0005004004,0.0007439995,0.0003577225,0.0002016987,0.0001293028,0.0001119151,0.0004197457,0.00008918284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001603861,"about_ca_system_score_gemma":0.0007358209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000355552,"about_ca_topic_score_gemma":0.000004863387,"domain_scores_codex":[0.9970487,0.0002313716,0.0007669839,0.0006879012,0.0007234955,0.0005415463],"domain_scores_gemma":[0.9975492,0.0001943218,0.0004009171,0.0005414311,0.000150369,0.001163707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0004978547,0.001468523,0.0004173941,0.01571625,0.02357439,0.0003884349,0.00006960058,7.801661e-8,2.650717e-7,0.00001676528,0.00007084075,0.9577796],"study_design_scores_gemma":[0.02137408,0.01196203,0.1933108,0.2816004,0.4212922,0.001009859,0.0002126918,0.0002828201,0.0002094245,0.001444904,0.06321167,0.004089165],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003354508,0.9913211,0.000006630348,0.00002036022,0.00005709103,0.004387671,0.0004146605,0.0001027271,0.0003351993],"genre_scores_gemma":[0.05575049,0.9429296,0.0000520241,0.00003614906,0.0001533565,0.000419901,0.0005371474,0.00008178045,0.00003958811],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9536905,"threshold_uncertainty_score":0.9997448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05210576642208294,"score_gpt":0.3658371210879258,"score_spread":0.3137313546658428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}