{"id":"W2327835887","doi":"10.1158/1538-7445.am2013-2376","title":"Abstract 2376: Improved progression-free survival (PFS) in patients with short tumor telomere length: Subgroup analysis from a randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced NSCLC .","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame","funders":"","keywords":"Telomerase; Telomere; Medicine; Internal medicine; Oncology; Biology; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003521691,0.001503535,0.004373906,0.0005667279,0.0003158925,0.001157094,0.0007465965,0.001171287,0.003724224],"category_scores_gemma":[0.002434696,0.0005081136,0.005541231,0.0005886116,0.0005324949,0.0007941145,0.0004661422,0.001729642,0.0004591273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00067706,"about_ca_system_score_gemma":0.000864215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000474659,"about_ca_topic_score_gemma":0.001097401,"domain_scores_codex":[0.9987544,0.0006175553,0.0001486212,0.0002253283,0.0001103362,0.0001438083],"domain_scores_gemma":[0.998993,0.0003454806,0.000235863,0.0001327042,0.00006959503,0.000223337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9630035,0.0007861558,0.008663552,0.0007815931,0.008413238,0.0000934539,0.00004745598,0.0005237859,0.004779178,0.00005573117,0.0006541319,0.01219811],"study_design_scores_gemma":[0.7257641,0.143807,0.07955816,0.0002170628,0.03897917,0.0003366027,0.0001576178,0.003242494,0.004133467,0.0007350867,0.002970181,0.0000990869],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866021,0.00864982,0.0006603608,0.0005107537,0.0003334933,0.0007932129,0.001625949,0.00005499138,0.0007692692],"genre_scores_gemma":[0.9948768,0.001169494,0.0004164787,0.0004257994,0.0003315209,0.0006229618,0.001296054,0.00001657851,0.0008442535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004373906,"threshold_uncertainty_score":0.01862472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02880326899768943,"score_gpt":0.3675628717224027,"score_spread":0.3387596027247133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}