{"id":"W2327888993","doi":"10.1021/bc1002604","title":"Impact of Epidermal Growth Factor Tethering Strategy on Cellular Response","year":2010,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal; National Research Council Canada; Biotechnology Research Institute","funders":"","keywords":"Chemistry; Epidermal growth factor; Adhesion; Biophysics; Cell adhesion; Grafting; Tethering; Substrate (aquarium); Cell; Receptor; Cell growth; Cell biology; Phosphorylation; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002100393,0.0002107076,0.0003067685,0.0000447116,0.00005292149,0.00001556526,0.0001589119,0.0001859129,0.00231912],"category_scores_gemma":[0.0002448938,0.0001530556,0.0002655952,0.0001073745,0.0002002034,0.000035354,0.00005486155,0.0005513738,0.00006602763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004049857,"about_ca_system_score_gemma":0.0002564919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001734113,"about_ca_topic_score_gemma":8.431538e-7,"domain_scores_codex":[0.9987559,0.00003123396,0.000270384,0.0002733622,0.0003103198,0.0003587861],"domain_scores_gemma":[0.9989654,0.0001700594,0.00008222229,0.0003394744,0.0001355393,0.0003073057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003210848,0.0001672657,0.01663698,0.0002201587,0.00009071259,0.0001150238,0.00004203727,0.000001496797,0.9783671,0.00002346944,0.0002048867,0.0009199846],"study_design_scores_gemma":[0.0006309227,0.0003752527,0.1073187,0.00005189058,0.00001130578,0.00005703971,0.00001766496,0.00004356363,0.8905894,0.00003791882,0.0007283486,0.0001379831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937497,0.00007054285,0.000002135444,0.0003256328,0.00004550837,0.0001516407,0.0001115254,0.00003366391,0.005509701],"genre_scores_gemma":[0.9958481,0.0000236561,0.0000821403,0.00003574276,0.0002646506,0.000007305505,0.00003394613,0.00002629746,0.003678197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09068175,"threshold_uncertainty_score":0.9985929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02893388833527076,"score_gpt":0.3300070862921937,"score_spread":0.3010731979569229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}