{"id":"W2327888993","doi":"10.1021/bc1002604","title":"Impact of Epidermal Growth Factor Tethering Strategy on Cellular Response","year":2010,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal; National Research Council Canada; Biotechnology Research Institute","funders":"","keywords":"Chemistry; Epidermal growth factor; Adhesion; Biophysics; Cell adhesion; Grafting; Tethering; Substrate (aquarium); Cell; Receptor; Cell growth; Cell biology; Phosphorylation; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001920265,0.0004210775,0.0002631623,0.0001381041,0.0001182354,0.0003667229,0.0001548258,0.0003328009,0.001017432],"category_scores_gemma":[0.0003094079,0.0001344117,0.0001112327,0.0001454289,0.0001482111,0.0001741665,0.0001984752,0.0002705842,0.0002218798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002459628,"about_ca_system_score_gemma":0.0001645368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006478714,"about_ca_topic_score_gemma":0.001047808,"domain_scores_codex":[0.9997576,0.00005346577,0.0000227406,0.00004765622,0.00005939754,0.00005914639],"domain_scores_gemma":[0.9997906,0.0001172874,0.00002473192,0.0000149082,0.00002653115,0.00002580621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000677783,0.00002014011,0.00006825838,0.00003309772,0.000004096733,0.00003533888,0.00001425349,0.00008866164,0.9988682,0.00002154373,0.00001508625,0.0007636251],"study_design_scores_gemma":[0.000004937573,0.0001634755,0.0006404816,0.000002060109,0.000008611256,0.00003547409,0.00001217913,0.0004372441,0.9982896,0.00000570873,0.00039739,0.000002776318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975334,0.000709744,0.000894959,0.00004091246,0.00002096138,0.0000185805,0.00006471281,0.00002833601,0.00068836],"genre_scores_gemma":[0.9974384,0.0005354061,0.001212975,0.00004508352,0.000008073423,0.00001970211,0.00009107903,0.00001317645,0.0006360094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001017432,"threshold_uncertainty_score":0.003403604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02893388833527076,"score_gpt":0.3300070862921937,"score_spread":0.3010731979569229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}