{"id":"W2327911874","doi":"10.1038/sj.cgt.7700195","title":"Combinational immunotherapy for established tumors with engineered tumor vaccines and adenovirus-mediated gene transfer","year":2000,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Medical Research Council","keywords":"Immunogenicity; Tumor necrosis factor alpha; Immunotherapy; CD8; Cancer research; Genetic enhancement; Cytotoxic T cell; Immune system; Cytokine; Biology; Immunology; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005764587,0.001109701,0.0009706685,0.001057259,0.0002504746,0.0007175591,0.0008248008,0.0007997878,0.00130724],"category_scores_gemma":[0.000279191,0.0003070959,0.0006670789,0.0006192441,0.0005930382,0.000742233,0.0005242457,0.001635802,0.0005052518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000616578,"about_ca_system_score_gemma":0.0006424614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005394825,"about_ca_topic_score_gemma":0.001065639,"domain_scores_codex":[0.9996005,0.00008536891,0.00002123797,0.0000675555,0.000122697,0.0001027162],"domain_scores_gemma":[0.9998416,0.00005190355,0.00002522752,0.00003963864,0.0000114679,0.00003020868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001749888,0.002531576,0.0008377588,0.0003457271,0.0001874393,0.0002049339,0.000109291,0.002662901,0.9421365,0.003722245,0.000807249,0.04470443],"study_design_scores_gemma":[0.0006169273,0.006477199,0.001801737,0.00002662074,0.0003035342,0.0008207554,0.00003253204,0.004129187,0.9733267,0.0006744467,0.0117658,0.00002446643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9271868,0.01726387,0.04497946,0.0004744917,0.0007628346,0.0009424548,0.0004054399,0.0005866805,0.007397981],"genre_scores_gemma":[0.9719824,0.005548333,0.01463182,0.00008701898,0.000159887,0.0005631073,0.0003791062,0.0000730808,0.006575253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00130724,"threshold_uncertainty_score":0.004473627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01171448116673684,"score_gpt":0.2634713458160522,"score_spread":0.2517568646493154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}