{"id":"W2327951769","doi":"10.1021/mp300099f","title":"Phase Separation Behavior of Fusidic Acid and Rifampicin in PLGA Microspheres","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Renishaw","keywords":"Fusidic acid; Rifampicin; PLGA; Microsphere; Chemistry; Chromatography; Antibiotics; Pharmacology; Microbiology; Medicine; Chemical engineering; Bacteria; Biochemistry; Biology; Staphylococcus aureus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002491792,0.0001076831,0.0001102848,0.00002853692,0.00002488148,0.000007898072,0.00008103502,0.000100013,0.00002298295],"category_scores_gemma":[0.00003751988,0.0001143379,0.00003924765,0.00008332375,0.00008636709,0.000006425156,0.00005203898,0.00008356717,0.000002556629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001137658,"about_ca_system_score_gemma":0.00002906018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007645965,"about_ca_topic_score_gemma":0.000006022229,"domain_scores_codex":[0.9992318,0.00009398762,0.0002188621,0.0001730024,0.0000911708,0.0001911829],"domain_scores_gemma":[0.9995708,0.00000395151,0.00007072867,0.0002193622,0.00004482812,0.00009031314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006778313,0.0005436908,0.01705697,0.00002458054,0.00001095335,0.000001516825,0.0001068407,0.000003136891,0.9748846,0.00008542436,0.00002300616,0.007191495],"study_design_scores_gemma":[0.00150806,0.00009293403,0.004057142,0.000003931261,0.00002816339,0.000007520715,0.00003900041,0.00007041589,0.9824073,0.00001514992,0.01165377,0.0001166325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987233,0.009851711,0.002222216,0.00004832471,0.00005949416,0.0003263033,0.00002229135,0.000006117822,0.0002305545],"genre_scores_gemma":[0.9984812,0.0002449492,0.0009116969,0.0001817611,0.00002860119,0.00004181309,0.00006313481,0.00001213435,0.00003477652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01299983,"threshold_uncertainty_score":0.4662565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02911754097426837,"score_gpt":0.3804601503941906,"score_spread":0.3513426094199222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}