{"id":"W2328028556","doi":"10.1097/pai.0000000000000082","title":"CytoLyt® Fixation and Decalcification Pretreatments Alter Antigenicity in Normal Tissues Compared With Standard Formalin Fixation","year":2014,"lang":"en","type":"article","venue":"Applied immunohistochemistry & molecular morphology","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Capital District Health Authority; Dalhousie University","funders":"","keywords":"Bone decalcification; Immunohistochemistry; Fixation (population genetics); Chromogranin A; Pathology; Chemistry; Medicine; Molecular biology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001712802,0.0008483733,0.0004400906,0.001101177,0.0006379429,0.0006284641,0.0005431949,0.0006140312,0.004577315],"category_scores_gemma":[0.001295386,0.0004449836,0.0003882365,0.0007255524,0.000907286,0.0005616653,0.0005183032,0.0009786083,0.00104331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005090063,"about_ca_system_score_gemma":0.0006306171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001255141,"about_ca_topic_score_gemma":0.002906658,"domain_scores_codex":[0.9985819,0.0001984436,0.0001787394,0.0004410851,0.0004331174,0.0001666801],"domain_scores_gemma":[0.9987367,0.0003885376,0.0002090821,0.0002661568,0.0003391479,0.00006036536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000153853,0.00003400376,0.001130769,0.000177322,0.00001591497,0.0001447951,0.00007964078,0.00005823033,0.99318,0.0002637477,0.0001717423,0.004590031],"study_design_scores_gemma":[0.00004775252,0.000718461,0.02033903,0.00009821644,0.0001432768,0.001974925,0.0001328606,0.0009897446,0.9575052,0.0003793009,0.01764593,0.0000254597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8263066,0.01606967,0.1368938,0.0007544237,0.0008255468,0.001163292,0.001084326,0.001352307,0.01555017],"genre_scores_gemma":[0.7326339,0.01221129,0.2244652,0.0009647424,0.0002184445,0.002614025,0.006281453,0.0009003813,0.01971059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004577315,"threshold_uncertainty_score":0.01531261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004989080031638438,"score_gpt":0.2523398426164398,"score_spread":0.2473507625848014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}