{"id":"W2328625892","doi":"10.1021/acs.analchem.5b02504","title":"Universal Strategy To Engineer Catalytic DNA Hairpin Assemblies for Protein Analysis","year":2015,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Brock University","funders":"Natural Sciences and Engineering Research Council of Canada; Brock University","keywords":"Chemistry; DNA; Catalysis; Nanotechnology; Computational biology; Biophysics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005179363,0.0006402596,0.0002967983,0.0004616294,0.0002384608,0.000365066,0.000516822,0.0006399833,0.000611551],"category_scores_gemma":[0.0003873184,0.000428287,0.0003615392,0.0003141036,0.0003835312,0.0004394226,0.0005658654,0.001061923,0.0004416418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004532831,"about_ca_system_score_gemma":0.0003748608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002767328,"about_ca_topic_score_gemma":0.0006446642,"domain_scores_codex":[0.999638,0.00005792427,0.00003195964,0.0001033727,0.0001029294,0.00006582723],"domain_scores_gemma":[0.9998593,0.00002335859,0.00003626302,0.00002083507,0.00003277272,0.00002738948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001636045,0.00004221683,0.00008428592,0.00008141248,0.000009483838,0.00008549858,0.00005878165,0.0003336405,0.9907197,0.002230617,0.0002114371,0.006126553],"study_design_scores_gemma":[0.000009365813,0.0001285807,0.0001056588,0.000005137321,0.000007453047,0.000122383,0.000008635411,0.001819217,0.9922058,0.0002166984,0.005361038,0.00001008914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4647984,0.005382744,0.5142993,0.0006294847,0.0004632751,0.0008664146,0.0005084095,0.001800065,0.01125189],"genre_scores_gemma":[0.8106704,0.002164962,0.181821,0.0003270515,0.0000375038,0.000465436,0.0004620256,0.0001136651,0.003937982],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.0006402596,"threshold_uncertainty_score":0.003288805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0186898381885138,"score_gpt":0.2873424164329299,"score_spread":0.2686525782444161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}