{"id":"W2328635643","doi":"10.1021/ja5070813","title":"Structure and Biosynthesis of Carnolysin, a Homologue of Enterococcal Cytolysin with <scp>d</scp>-Amino Acids","year":2014,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Cytolysin; Chemistry; Biosynthesis; Amino acid; Biochemistry; Microbiology; Gene; Virulence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001600025,0.0001216974,0.0004127911,0.000006036068,0.00004995146,0.00001244524,0.000351532,0.00006882119,0.000005268292],"category_scores_gemma":[0.0001078379,0.00003716369,0.0002830206,0.0002883016,0.0006757007,0.00003766118,0.0001121121,0.0002243892,8.341532e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002109932,"about_ca_system_score_gemma":0.00001107075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003763531,"about_ca_topic_score_gemma":0.000003726924,"domain_scores_codex":[0.9991214,0.00006184534,0.0002961188,0.0001199689,0.0002327368,0.0001679802],"domain_scores_gemma":[0.9987093,0.0002850548,0.0007459847,0.00006955856,0.0001110216,0.00007910936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002470739,0.00006456984,0.0176412,0.00001063622,0.0001065872,3.405682e-7,0.0001488937,0.00000210969,0.976735,0.00001458911,0.0002292339,0.005022143],"study_design_scores_gemma":[0.0002322301,0.0007223091,0.1057882,0.00006343684,0.0001192077,0.00006021096,0.0008210006,0.00005906579,0.8911853,0.0002274191,0.0006632033,0.00005836654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992681,0.00006995697,0.00001800996,0.0005085183,0.00002497447,0.00004599979,0.00003001694,0.000003527031,0.00003085596],"genre_scores_gemma":[0.9986658,0.00004970797,0.001008515,0.0001731242,0.00008985679,3.2843e-7,0.000001469073,0.000001376446,0.000009842266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.088147,"threshold_uncertainty_score":0.2489647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005440585141528775,"score_gpt":0.1866665870239907,"score_spread":0.1812260018824619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}