{"id":"W2328660396","doi":"10.1097/01.qai.0000397409.60275.47","title":"227 Kinome Profiling of Bovine Leukemia Virus-induced Ovine Leukemia: An Approach for Identifying Altered Signaling Pathways and Drugable Targets in Cancer","year":2011,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Kinome; Leukemia; Biology; Cancer research; Cancer; Phosphorylation; Cell signaling; Cancer cell; Signal transduction; Computational biology; Cell; Cell biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014757,0.0001136114,0.0001847351,0.0005538107,0.0001813721,0.0002852165,0.00007938065,0.0001670746,0.0008215549],"category_scores_gemma":[0.0001392245,0.00006506278,0.0001318583,0.0002865608,0.0001149837,0.0001509623,0.0001324811,0.0002167847,0.0001964735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002330461,"about_ca_system_score_gemma":0.00008866803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008102013,"about_ca_topic_score_gemma":0.001775968,"domain_scores_codex":[0.9999236,0.00001413335,0.000005269826,0.00001586003,0.00002569522,0.00001546628],"domain_scores_gemma":[0.9999276,0.00001660961,0.00002483352,0.000007471971,0.00001112694,0.00001243965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000460117,0.000004619349,0.0005737573,0.00001165075,0.000002496873,0.00001786835,0.000007724784,0.00003153876,0.9984701,0.00001739692,0.000009508562,0.0008073027],"study_design_scores_gemma":[0.000008809599,0.0002853177,0.07309948,0.000005700742,0.00002935222,0.0006815078,0.00008522363,0.00194415,0.9214733,0.0001348032,0.002242949,0.000009424992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901547,0.001145981,0.00657942,0.00004270962,0.000006838285,0.00003122299,0.001031609,0.00004814793,0.00095929],"genre_scores_gemma":[0.9909263,0.000602858,0.006283536,0.00003903278,0.000003093499,0.00002861476,0.001176558,0.00001188132,0.0009280825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008215549,"threshold_uncertainty_score":0.00274837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06998590241678036,"score_gpt":0.277171518442822,"score_spread":0.2071856160260416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}