{"id":"W2328746349","doi":"10.1021/jf404738s","title":"Esterification Enhanced Intestinal Absorption of Ginsenoside Rh2 in Caco-2 Cells without Impacts on Its Protective Effects against H<sub>2</sub>O<sub>2</sub>-Induced Cell Injury in Human Umbilical Vein Endothelial Cells (HUVECs)","year":2014,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Ginseng Biological Effects and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Caco-2; Chemistry; Umbilical vein; Oxidative stress; Apoptosis; Transcellular; Bioavailability; Flow cytometry; In vitro; Absorption (acoustics); Ginsenoside; Pharmacology; Biochemistry; Molecular biology; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001205697,0.0004309712,0.0003346909,0.0001207834,0.00008258579,0.0002001592,0.0001133398,0.0002221137,0.000919188],"category_scores_gemma":[0.000112101,0.0001452684,0.0003844916,0.0001723016,0.0001327467,0.0003692397,0.0001715954,0.000386089,0.0002177216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001384195,"about_ca_system_score_gemma":0.0001431521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007211871,"about_ca_topic_score_gemma":0.001130732,"domain_scores_codex":[0.9998939,0.00001778953,0.00001347584,0.00002704644,0.00002312866,0.00002468372],"domain_scores_gemma":[0.9999572,0.000006468802,0.00001445176,0.000006760097,0.000008010424,0.000007210959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002115092,0.00001541764,0.00007271677,0.000049866,0.000005724014,0.00003398569,0.000009227037,0.00004023567,0.9986922,0.00002841282,0.00001465278,0.0008260646],"study_design_scores_gemma":[0.00001239778,0.0003232165,0.001137135,0.000003534208,0.00002068499,0.0000633879,0.00001606846,0.000236385,0.9966652,0.00001091195,0.001506331,0.000004851197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995019,0.001205711,0.002050796,0.00005279518,0.00002708777,0.00002994702,0.0002992106,0.0000428865,0.001272576],"genre_scores_gemma":[0.9904383,0.001503709,0.003777586,0.00009242275,0.00001584092,0.00004713578,0.000521236,0.00003699687,0.003566922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000919188,"threshold_uncertainty_score":0.003075004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007310163635257726,"score_gpt":0.2226240643698189,"score_spread":0.2153139007345612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}