{"id":"W2328746349","doi":"10.1021/jf404738s","title":"Esterification Enhanced Intestinal Absorption of Ginsenoside Rh2 in Caco-2 Cells without Impacts on Its Protective Effects against H<sub>2</sub>O<sub>2</sub>-Induced Cell Injury in Human Umbilical Vein Endothelial Cells (HUVECs)","year":2014,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Ginseng Biological Effects and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Caco-2; Chemistry; Umbilical vein; Oxidative stress; Apoptosis; Transcellular; Bioavailability; Flow cytometry; In vitro; Absorption (acoustics); Ginsenoside; Pharmacology; Biochemistry; Molecular biology; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002762148,0.0002937764,0.0003982025,0.00004986388,0.00006336922,0.00003117157,0.0001793215,0.0003258079,5.895875e-7],"category_scores_gemma":[0.0001306381,0.0002006462,0.0001331583,0.0001564003,0.00007425113,0.00001864368,0.00005589625,0.000478194,0.000001743198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006814484,"about_ca_system_score_gemma":0.00004437458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005056875,"about_ca_topic_score_gemma":0.00001259243,"domain_scores_codex":[0.998462,0.000134852,0.0005635289,0.0003721023,0.0001861528,0.0002813678],"domain_scores_gemma":[0.998873,0.00006936811,0.0005562906,0.0001593281,0.000178503,0.0001634947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002129677,0.0003915809,0.00009067432,0.0002003434,0.00002010422,0.000001512449,0.00006876529,0.0001245947,0.9966188,0.000002504554,0.00002073585,0.00224743],"study_design_scores_gemma":[0.001230301,0.002204075,0.02880238,0.0002765955,0.00002067059,0.00001974873,0.00005875315,0.00001960373,0.9670771,0.00002737452,0.000008175267,0.000255224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992294,0.00004655192,0.00004919825,0.00005890427,0.00005112857,0.0004406684,0.00001953343,0.000008009085,0.00009660517],"genre_scores_gemma":[0.9994234,0.0001183988,0.00004737248,0.00004502244,0.0002645844,0.00004377113,0.00003858668,0.00001395097,0.000004870045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02954169,"threshold_uncertainty_score":0.8182114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007310163635257726,"score_gpt":0.2226240643698189,"score_spread":0.2153139007345612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}