{"id":"W2328763062","doi":"10.1038/icb.2014.68","title":"Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells","year":2014,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; Newfoundland and Labrador","keywords":"CD8; Biology; Cytotoxic T cell; TIGIT; Immunology; Ex vivo; Human leukocyte antigen; T cell; Antigen; Molecular biology; Immune system; In vivo; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001020273,0.0008503824,0.001320083,0.001011026,0.0005545319,0.00003698794,0.0003993795,0.00225961,0.002997728],"category_scores_gemma":[0.0002765269,0.0007931856,0.0003633092,0.0006005552,0.001193787,0.0004446135,0.0003036603,0.001943892,0.001308958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002438216,"about_ca_system_score_gemma":0.0001604291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001550193,"about_ca_topic_score_gemma":0.00008153335,"domain_scores_codex":[0.9936792,0.002308152,0.001378429,0.001336576,0.00008606214,0.001211553],"domain_scores_gemma":[0.9975442,0.0006435778,0.0005729622,0.0008558744,0.0003131904,0.00007016037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004997839,0.0007167247,0.0101037,0.0001339368,0.0006753635,0.000005362365,0.002464919,0.002309317,0.9623113,0.001225402,0.00181934,0.01323684],"study_design_scores_gemma":[0.01227969,0.008213781,0.0207536,0.0002095204,0.0004671812,0.0002890211,0.002638651,0.004360016,0.6111279,0.001647588,0.3361982,0.001814877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867085,0.003721185,0.001945121,0.0002403993,0.002018146,0.001104977,0.00003862112,0.000239178,0.003983863],"genre_scores_gemma":[0.992542,0.001109667,0.0000746614,0.0005519961,0.0001866292,0.0002436024,0.0005377496,0.00008299193,0.004670667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3511834,"threshold_uncertainty_score":0.9994686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006958998311303161,"score_gpt":0.2173878964415211,"score_spread":0.210428898130218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}