{"id":"W2328763062","doi":"10.1038/icb.2014.68","title":"Protective genotypes in HIV infection reflect superior function of KIR3DS1<sup>+</sup> over KIR3DL1<sup>+</sup> CD8<sup>+</sup> T cells","year":2014,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; Newfoundland and Labrador","keywords":"CD8; Biology; Cytotoxic T cell; TIGIT; Immunology; Ex vivo; Human leukocyte antigen; T cell; Antigen; Molecular biology; Immune system; In vivo; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009198354,0.0001850168,0.0001645037,0.0002159756,0.0001755536,0.0003029211,0.00009636321,0.000215597,0.002387743],"category_scores_gemma":[0.0001868558,0.0001209685,0.0001094353,0.0001486266,0.0001810407,0.0001255916,0.0001870666,0.0003325726,0.0003143052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009681554,"about_ca_system_score_gemma":0.00008291247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002700316,"about_ca_topic_score_gemma":0.0003197863,"domain_scores_codex":[0.9999049,0.00001374649,0.00001087781,0.00002464121,0.00001310969,0.00003275222],"domain_scores_gemma":[0.9998616,0.00002582986,0.00004042904,0.00001596133,0.00001113828,0.00004514174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001085625,0.00007389952,0.02721297,0.00004345871,0.00001687527,0.0003497366,0.0001320787,0.00007951371,0.9659463,0.0001227398,0.00006321293,0.00487348],"study_design_scores_gemma":[0.0001306386,0.003058877,0.7135051,0.00005337335,0.0001581139,0.01464226,0.000782998,0.001471149,0.2623472,0.0007674519,0.003048595,0.0000343247],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994938,0.0001169649,0.00009781671,0.000007209027,0.00000207256,0.000003146455,0.00006895181,0.000005218878,0.0002048349],"genre_scores_gemma":[0.9992932,0.00008269377,0.0001536482,0.00001597005,0.000003513974,0.000006050251,0.0001136855,0.000005717488,0.000325563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002387743,"threshold_uncertainty_score":0.007987738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006958998311303161,"score_gpt":0.2173878964415211,"score_spread":0.210428898130218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}