{"id":"W2328765069","doi":"10.1097/ftd.0000000000000072","title":"A Specific and Sensitive HPLC–MS/MS Micromethod for Milrinone Plasma Levels Determination After Inhalation in Cardiac Patients","year":2014,"lang":"en","type":"article","venue":"Therapeutic Drug Monitoring","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Milrinone; Chromatography; Pharmacokinetics; Inhalation; Chemistry; Ammonium acetate; High-performance liquid chromatography; Coefficient of variation; Electrospray ionization; Anesthesia; Mass spectrometry; Medicine; Pharmacology; Hemodynamics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001041377,0.000858595,0.0005794176,0.001013485,0.0003425748,0.0006057944,0.0006058946,0.001019249,0.001510903],"category_scores_gemma":[0.001592714,0.0003289093,0.0003881529,0.0003600949,0.0004319688,0.0003465743,0.0004385863,0.0009632623,0.0008766735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002997395,"about_ca_system_score_gemma":0.000690299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002486214,"about_ca_topic_score_gemma":0.000755762,"domain_scores_codex":[0.9983805,0.0003232575,0.0001609692,0.0003938676,0.0006635832,0.0000777621],"domain_scores_gemma":[0.9992939,0.0001894627,0.0002103406,0.00007297058,0.000172595,0.0000606078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001425323,0.0004848254,0.04066199,0.0006286253,0.0002029514,0.0007581952,0.0002364664,0.0006508295,0.8663398,0.0004223495,0.002093807,0.08609484],"study_design_scores_gemma":[0.0002023713,0.004721324,0.102125,0.0001909017,0.0002900827,0.01042851,0.0001727163,0.01095997,0.8551458,0.0004761883,0.01516294,0.0001242357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7720506,0.01884621,0.1905037,0.001421969,0.0006072772,0.001670611,0.003772256,0.003106079,0.008021393],"genre_scores_gemma":[0.8897576,0.003545775,0.09844019,0.001528045,0.0002587803,0.001234553,0.001391047,0.0001030169,0.003741019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001510903,"threshold_uncertainty_score":0.00550741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02620989540050776,"score_gpt":0.288594491601976,"score_spread":0.2623845962014683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}