{"id":"W2328965374","doi":"10.1006/mthe.2002.0570","title":"Improved Treatment of Pancreatic Cancer by IL-12 and B7.1 Costimulation: Antitumor Efficacy and Immunoregulation in a Nonimmunogenic Tumor Model","year":2002,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Pancreatic cancer; Immune system; Immunotherapy; Medicine; Downregulation and upregulation; Adenocarcinoma; Cancer research; Cancer; Immunology; Oncology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009135115,0.0002543144,0.0004182141,0.000127737,0.0001079513,0.00001866416,0.0000894566,0.0001254436,0.0001558981],"category_scores_gemma":[0.00001078647,0.0002197092,0.00007166152,0.0001218727,0.0002049443,0.00008874751,0.00001725138,0.00008755755,0.000004930618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006132515,"about_ca_system_score_gemma":0.00002525473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003693632,"about_ca_topic_score_gemma":0.000008838524,"domain_scores_codex":[0.9988524,0.000193992,0.0003602758,0.0002882407,0.0000371967,0.0002679037],"domain_scores_gemma":[0.9994304,0.0000812026,0.0001451903,0.0002941504,0.00003441711,0.00001460873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00161591,0.0003521663,0.001188648,0.000009024145,0.0002928405,0.000003363284,0.00111428,0.0001677418,0.9547977,0.00002523284,0.00001270688,0.0404204],"study_design_scores_gemma":[0.01766806,0.001637734,0.0222082,0.00008120017,0.0000701322,0.00005674231,0.00005692783,0.007919097,0.9478401,0.00004890153,0.002023436,0.0003894684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8271696,0.1717822,0.000287675,0.0001009574,0.00004719927,0.000535954,0.00003126396,0.00002083384,0.00002425637],"genre_scores_gemma":[0.9831994,0.01569618,0.00009538946,0.00009607774,0.000003969933,0.00008543662,0.00003893192,0.00003026724,0.0007543437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1560861,"threshold_uncertainty_score":0.8959481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01490666889580862,"score_gpt":0.2449258660001229,"score_spread":0.2300191971043143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}