{"id":"W2328965374","doi":"10.1006/mthe.2002.0570","title":"Improved Treatment of Pancreatic Cancer by IL-12 and B7.1 Costimulation: Antitumor Efficacy and Immunoregulation in a Nonimmunogenic Tumor Model","year":2002,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Pancreatic cancer; Immune system; Immunotherapy; Medicine; Downregulation and upregulation; Adenocarcinoma; Cancer research; Cancer; Immunology; Oncology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003561903,0.0008616039,0.000654216,0.000631958,0.0001814735,0.0003544805,0.0004935617,0.0005245428,0.0007598045],"category_scores_gemma":[0.0001344387,0.0001572118,0.0003556059,0.000272289,0.0004562274,0.0004336964,0.0002257588,0.00156137,0.0002690822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003488556,"about_ca_system_score_gemma":0.000315142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003389765,"about_ca_topic_score_gemma":0.0003930673,"domain_scores_codex":[0.9996089,0.00009486479,0.00003372008,0.00006093598,0.00009850633,0.0001030296],"domain_scores_gemma":[0.9998491,0.00002517817,0.0000441004,0.00001911064,0.00001347307,0.00004898211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007239297,0.0008924731,0.000134936,0.00008906311,0.00001045502,0.00005153805,0.00002272026,0.0002414219,0.9940533,0.0001948555,0.00008925058,0.003496025],"study_design_scores_gemma":[0.0001540267,0.003805672,0.001021379,0.000007376759,0.00003390456,0.000191572,0.00001465399,0.001371687,0.991793,0.00005597279,0.001544819,0.000005908154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929591,0.00218613,0.003057402,0.0001763396,0.00008716341,0.000115215,0.0001760413,0.0001357512,0.00110683],"genre_scores_gemma":[0.9913898,0.001613657,0.004032977,0.00008206909,0.0000656661,0.0002291557,0.0003822,0.0000391602,0.002165244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008616039,"threshold_uncertainty_score":0.00254184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01490666889580862,"score_gpt":0.2449258660001229,"score_spread":0.2300191971043143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}