{"id":"W2328985452","doi":"10.1097/00054725-200912002-00172","title":"The A4-Fla2 flagellin, a dominant antigen in Crohnʼs Disease, is a poor TLR5 agonist","year":2009,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Crohn's and Colitis Foundation of America","keywords":"TLR5; Flagellin; Immunology; Microbiology; Antigen; Biology; Colitis; Antibody; Inflammatory bowel disease; Receptor; Medicine; Toll-like receptor; Immune system; Internal medicine; Disease; Innate immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000234942,0.0002939594,0.0002856674,0.0002792269,0.0002302017,0.0002166137,0.0001138209,0.0004624854,0.002169282],"category_scores_gemma":[0.0002329101,0.00009560207,0.0001412012,0.0001855464,0.0001668216,0.0001846678,0.0001843546,0.0003382871,0.0005566303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002568915,"about_ca_system_score_gemma":0.0001277734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006019197,"about_ca_topic_score_gemma":0.0006962672,"domain_scores_codex":[0.9998757,0.00003188579,0.00001210167,0.00002326948,0.00002547489,0.0000314746],"domain_scores_gemma":[0.9999043,0.00001615033,0.00002314086,0.00000449184,0.00001123782,0.00004070666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004543272,0.0004636204,0.04990696,0.0004019611,0.00005733511,0.001971027,0.00005566408,0.0001111804,0.8819513,0.0001913585,0.002508224,0.0578381],"study_design_scores_gemma":[0.0009358678,0.01595061,0.5719485,0.0002098662,0.0002949232,0.03697165,0.0004521879,0.001954264,0.3038892,0.0005625474,0.06677289,0.00005759968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809051,0.01486383,0.0008483194,0.0006252871,0.00007122914,0.00002346607,0.0002536789,0.00006406238,0.002345128],"genre_scores_gemma":[0.9943238,0.002033484,0.0008719768,0.0003431585,0.00007544257,0.00001976976,0.0004863709,0.000006097823,0.001839805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002169282,"threshold_uncertainty_score":0.007256985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005744706625580524,"score_gpt":0.2339592854435725,"score_spread":0.228214578817992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}