{"id":"W2329049402","doi":"10.3389/fgene.2016.00040","title":"Mouse Genetic Models of Human Brain Disorders","year":2016,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Sick Kids Foundation","keywords":"Biology; Computational biology; Human brain; Neuroscience; Genetics; Evolutionary biology; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001466001,0.0006190005,0.001144921,0.0003341625,0.00005759326,0.00001789905,0.0008283814,0.0006030096,0.00001253112],"category_scores_gemma":[0.00002878335,0.0005624475,0.0004505055,0.0002382656,0.0002446561,0.000002769011,0.0003732994,0.0001959648,0.000006347245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004758124,"about_ca_system_score_gemma":0.0002574545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006438558,"about_ca_topic_score_gemma":0.00004502938,"domain_scores_codex":[0.9971871,0.0001876763,0.0009676145,0.0008460822,0.0002659068,0.0005455628],"domain_scores_gemma":[0.9985457,0.00001507957,0.0003937352,0.0008699032,0.00004572383,0.0001298511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001311995,0.0001663649,0.0003414686,0.00284609,0.0002347859,0.000003230449,0.00004478827,0.0001784431,0.002400855,0.00002486046,0.01609883,0.9776472],"study_design_scores_gemma":[0.0006469943,0.0003196483,0.0001251156,0.001198582,0.0001172391,0.000004995092,0.00002920601,0.00003473976,0.0004664735,0.001195572,0.9949566,0.0009049005],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001639546,0.9919945,0.004212091,0.0000168356,0.0004916618,0.0008226918,0.00015587,0.00001046027,0.000656353],"genre_scores_gemma":[0.0006047812,0.9914509,0.006052069,0.00005123475,0.00004997317,0.0001004912,0.0002506233,0.0001735263,0.00126638],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9788577,"threshold_uncertainty_score":0.9996827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01719229134569842,"score_gpt":0.2709179387843226,"score_spread":0.2537256474386242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}