{"id":"W2329049402","doi":"10.3389/fgene.2016.00040","title":"Mouse Genetic Models of Human Brain Disorders","year":2016,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Sick Kids Foundation","keywords":"Biology; Computational biology; Human brain; Neuroscience; Genetics; Evolutionary biology; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008754027,0.001159978,0.001154127,0.001609651,0.0002570898,0.0006880223,0.001345794,0.001239793,0.005092452],"category_scores_gemma":[0.0004518459,0.0002361162,0.000458352,0.0009029184,0.000780809,0.0006946198,0.0007190264,0.001851626,0.003376959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005603872,"about_ca_system_score_gemma":0.0007242769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007110318,"about_ca_topic_score_gemma":0.001031353,"domain_scores_codex":[0.9997014,0.00005632019,0.00003461656,0.00005047017,0.0001251682,0.00003206862],"domain_scores_gemma":[0.99983,0.00006250561,0.00003049928,0.00001350253,0.00004328592,0.00002018234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002420881,0.0002218356,0.0005468344,0.01323402,0.000161693,0.001922126,0.0001616376,0.0007122236,0.06347229,0.03895639,0.1022343,0.7781345],"study_design_scores_gemma":[0.0000266428,0.00008828023,0.0005771185,0.001131683,0.00007356272,0.004011387,0.00002665607,0.00007208831,0.004207755,0.004193509,0.9855711,0.00002011503],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001411123,0.9756451,0.004843478,0.0009248662,0.0007859788,0.00007931876,0.0004493757,0.0002070598,0.01565375],"genre_scores_gemma":[0.007289515,0.9804916,0.003745363,0.001012374,0.0002142387,0.0001369457,0.0007598862,0.00003099491,0.006318924],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005092452,"threshold_uncertainty_score":0.0170359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01719229134569842,"score_gpt":0.2709179387843226,"score_spread":0.2537256474386242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}