{"id":"W2329268420","doi":"10.1158/1538-7445.am10-4347","title":"Abstract 4347: Medulloblastoma comprises four distinct diseases","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medulloblastoma; Wnt signaling pathway; Biology; Isochromosome; CDKN2B; Genetics; Oncology; PTCH1; Cancer; Cancer research; Internal medicine; Chromosome; Gene; CDKN2A; Medicine; Sonic hedgehog; Karyotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002946443,0.0004961927,0.0005565107,0.001172564,0.0005592606,0.0006917676,0.0002886794,0.0003170475,0.002930805],"category_scores_gemma":[0.0006187963,0.0001907933,0.0004076544,0.001124428,0.0003239099,0.0003490926,0.0007151755,0.0004729518,0.0008436349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006630449,"about_ca_system_score_gemma":0.0007579511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003701934,"about_ca_topic_score_gemma":0.003877827,"domain_scores_codex":[0.9997373,0.00003024214,0.00003622721,0.00008840016,0.00006822571,0.00003961032],"domain_scores_gemma":[0.9998283,0.00002303593,0.00006344092,0.00001726312,0.00002812227,0.0000398245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001056514,0.00009985654,0.7577744,0.0002934563,0.0002835628,0.002692425,0.0005659941,0.0004526346,0.1675839,0.002447127,0.004487964,0.06226229],"study_design_scores_gemma":[0.00004329925,0.0002026455,0.9661101,0.00006590276,0.0002138732,0.01067069,0.0003031053,0.000898348,0.009459958,0.00173898,0.01027766,0.00001539166],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.986795,0.003180936,0.00302116,0.00044636,0.00004292633,0.0001137311,0.002312629,0.0001890618,0.003898162],"genre_scores_gemma":[0.9877833,0.001409576,0.004405858,0.0002743086,0.00006798244,0.00007800471,0.003781006,0.00008050864,0.002119551],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.003701934,"threshold_uncertainty_score":0.009804487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0547668177119091,"score_gpt":0.3901079709490914,"score_spread":0.3353411532371823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}