{"id":"W2329360889","doi":"10.1021/ac403762s","title":"Ultrasensitive DNAzyme Beacon for Lanthanides and Metal Speciation","year":2014,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Deoxyribozyme; Lanthanide; Chemistry; Metal; Metal ions in aqueous solution; Genetic algorithm; Divalent; Inorganic chemistry; Detection limit; Ion; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001505309,0.0001212111,0.000156139,0.00001234594,0.0000559234,0.00001675982,0.00004916237,0.0001344459,0.000003241061],"category_scores_gemma":[0.0003205745,0.0001065593,0.00009783663,0.00004428419,0.0001002553,0.000002769639,0.00002953158,0.00005385695,8.269323e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008569364,"about_ca_system_score_gemma":0.00001020382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002424159,"about_ca_topic_score_gemma":0.000002701875,"domain_scores_codex":[0.9993082,0.0000140572,0.0001362242,0.000307509,0.0000739285,0.0001600366],"domain_scores_gemma":[0.9995887,0.000040245,0.00005274086,0.0001606183,0.00008416256,0.00007356353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003838937,0.00002419821,0.0003589444,0.00001917878,0.00006399978,5.407641e-7,0.000002609266,9.718212e-7,0.9959916,0.0001316458,0.0005096106,0.002858267],"study_design_scores_gemma":[0.0001930066,0.00007338816,0.0002766952,0.000009150016,0.00009167012,0.00001369618,0.0000279894,0.0009212894,0.9907185,0.0003219269,0.007196017,0.0001566959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812468,0.00007571005,0.0141738,0.0002782955,0.00001467087,0.00008381218,0.00003646378,0.0000362114,0.004054292],"genre_scores_gemma":[0.9960912,0.00004682245,0.002138626,0.0001933541,0.0003649733,0.000003829063,0.0002395968,0.00001123281,0.0009103511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01484447,"threshold_uncertainty_score":0.434536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0072084174206729,"score_gpt":0.259226905084081,"score_spread":0.2520184876634081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}