{"id":"W2329465541","doi":"10.1158/0008-5472.sabcs-5118","title":"Phase II trial of neoadjuvant chemotherapy of sequential FEC100 followed by docetaxel, carboplatin and trastuzumab (TCH) for HER-2 over-expressing locally advanced breast cancer (LABC): a multi-centre study from British Columbia.","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kelowna General Hospital; BC Cancer Agency","funders":"","keywords":"Trastuzumab; Medicine; Docetaxel; Carboplatin; Breast cancer; Internal medicine; Epirubicin; Oncology; Chemotherapy; Cancer; Surgery; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002062159,0.001894534,0.002398781,0.0006739635,0.0009466846,0.00104381,0.00180508,0.00183292,0.004525408],"category_scores_gemma":[0.001138477,0.001005095,0.0007928503,0.0007724951,0.001617728,0.0006378635,0.0006057171,0.003179573,0.001252191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002963361,"about_ca_system_score_gemma":0.006097996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02593,"about_ca_topic_score_gemma":0.06853896,"domain_scores_codex":[0.9992517,0.0003361409,0.00002979249,0.0001264148,0.00008408829,0.0001718838],"domain_scores_gemma":[0.9982182,0.0001903722,0.0001838131,0.0001527772,0.0001363649,0.001118425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8365332,0.09087915,0.006685548,0.0004163046,0.0007154165,0.0003360419,0.0002941719,0.001151637,0.02516106,0.0000684238,0.002095618,0.0356634],"study_design_scores_gemma":[0.6126899,0.3596162,0.0224032,0.00003125874,0.0003438735,0.0001999641,0.00008162518,0.0005475511,0.001865076,0.00008409642,0.002093187,0.00004409421],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898862,0.0007311938,0.0003190275,0.0003912878,0.00007200413,0.005767174,0.0009972822,0.00007772476,0.001758118],"genre_scores_gemma":[0.9797537,0.001175759,0.001789739,0.001116942,0.0001198846,0.006404455,0.003226221,0.0000438432,0.006369531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02593,"threshold_uncertainty_score":0.05155814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05717163578144839,"score_gpt":0.4410339780599853,"score_spread":0.3838623422785369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}