{"id":"W2329559969","doi":"10.1021/cb300187t","title":"Quantitative Synthesis of Genetically Encoded Glycopeptide Libraries Displayed on M13 Phage","year":2012,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"","keywords":"Phage display; Glycopeptide; Combinatorial chemistry; Phagemid; Peptide library; Moiety; Peptide; Chemistry; Computational biology; Biology; Biochemistry; Peptide sequence; Bacteriophage; Gene; Stereochemistry; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002039963,0.0001808602,0.0002553086,0.00005674856,0.00004325019,0.000009861757,0.000297385,0.0003033525,0.0001721881],"category_scores_gemma":[0.001292035,0.0001475343,0.0001008491,0.0001232192,0.0004035678,0.000007605234,0.00019801,0.0001434936,0.00008967195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000109559,"about_ca_system_score_gemma":0.00005373916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001176017,"about_ca_topic_score_gemma":0.000001702894,"domain_scores_codex":[0.9986727,0.000148489,0.0002912424,0.000315247,0.0001285631,0.0004437299],"domain_scores_gemma":[0.9990674,0.0002332627,0.0000881387,0.0003559257,0.000085849,0.0001694506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006248986,0.0001794483,0.001832759,0.00001702744,0.00006724981,7.567497e-7,0.00003347947,0.000001624397,0.9849858,0.008281616,0.0007214966,0.003253806],"study_design_scores_gemma":[0.0003455313,0.0004261054,0.000550905,0.00001075954,0.00001205758,0.000004459323,0.00003326887,0.00002024595,0.9894389,0.0003096172,0.008682648,0.0001655361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928545,0.0005930458,0.0005998507,0.0002519237,0.00006895333,0.0001965969,0.00006964473,0.00001450798,0.005350937],"genre_scores_gemma":[0.9952415,0.0001117385,0.00381286,0.000248746,0.0001425955,0.00005961417,0.0001725131,0.00002061533,0.0001898443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007971999,"threshold_uncertainty_score":0.6016272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02148387986354587,"score_gpt":0.3028528713566122,"score_spread":0.2813689914930663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}