{"id":"W2329559969","doi":"10.1021/cb300187t","title":"Quantitative Synthesis of Genetically Encoded Glycopeptide Libraries Displayed on M13 Phage","year":2012,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"","keywords":"Phage display; Glycopeptide; Combinatorial chemistry; Phagemid; Peptide library; Moiety; Peptide; Chemistry; Computational biology; Biology; Biochemistry; Peptide sequence; Bacteriophage; Gene; Stereochemistry; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007110843,0.0007200111,0.0005295345,0.0003582235,0.000164991,0.0004948553,0.0004029882,0.0003775443,0.0006271797],"category_scores_gemma":[0.0005671735,0.0002654446,0.0003107349,0.0005441381,0.0003183812,0.0002684836,0.0003530194,0.0007215673,0.0004219444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003970128,"about_ca_system_score_gemma":0.000306563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002835109,"about_ca_topic_score_gemma":0.0008043921,"domain_scores_codex":[0.9994702,0.000126865,0.00004345093,0.00009444814,0.0001948998,0.0000700625],"domain_scores_gemma":[0.9996629,0.0001100822,0.00008142173,0.00003681645,0.00006795634,0.00004095376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002082774,0.000009034902,0.00003606063,0.00002766487,0.000003850269,0.00001173604,0.00000718231,0.0000933928,0.9985818,0.00006069285,0.00001295097,0.001134843],"study_design_scores_gemma":[0.000002893747,0.00005265094,0.000206709,0.000002290929,0.000006415517,0.00001901803,0.000003017806,0.0003936498,0.9988049,0.00001522855,0.0004910357,0.000002298308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8283836,0.001212911,0.164873,0.00007913451,0.00005755517,0.0004746885,0.00143281,0.0008341958,0.002652076],"genre_scores_gemma":[0.7793366,0.002579949,0.2081919,0.0001325166,0.00002990465,0.000464484,0.002849156,0.0003706999,0.006044801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007200111,"threshold_uncertainty_score":0.003760636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02148387986354587,"score_gpt":0.3028528713566122,"score_spread":0.2813689914930663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}