{"id":"W2329745319","doi":"10.1055/s-0033-1348566","title":"The Sesquiterpene Lactone Dehydroleucodine Shows Potent Anti-Leukemic Activity","year":2013,"lang":"en","type":"article","venue":"Planta Medica","topic":"Sesquiterpenes and Asteraceae Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Moiety; Sesquiterpene; Sesquiterpene lactone; Stereochemistry; Lactone; Methylene; Adduct; Chemistry; Conjugate; Conjugated system; Stereoselectivity; Biochemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005571518,0.0001990607,0.0001694234,0.000118246,0.00006932502,0.0001435446,0.00008428802,0.00009466081,0.001251507],"category_scores_gemma":[0.00005998978,0.00005439628,0.000062977,0.0001149914,0.0001041768,0.0001058529,0.0001036068,0.0001510664,0.0002167893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008564082,"about_ca_system_score_gemma":0.00007857497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002619509,"about_ca_topic_score_gemma":0.0005588034,"domain_scores_codex":[0.9999787,0.000004238359,0.000002113227,0.000004230302,0.000005290849,0.000005520918],"domain_scores_gemma":[0.9999686,0.000005564301,0.00000725739,0.000004041399,0.000004564698,0.000009962063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008638846,0.00001429208,0.0003878129,0.00003171644,0.000002850875,0.00006609561,0.00001323754,0.00007361842,0.9962454,0.00002412225,0.00001104334,0.003043347],"study_design_scores_gemma":[0.00003822358,0.0009277778,0.008898946,0.000006180109,0.00001666142,0.0004061639,0.00002764647,0.0002453605,0.9843353,0.00002860486,0.005063812,0.00000521137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996501,0.001710579,0.00047586,0.00003504023,0.000003957085,0.000008706489,0.0001245205,0.00002304222,0.001117418],"genre_scores_gemma":[0.9978897,0.0006218108,0.0004210184,0.00001451078,0.000003117383,0.000004478427,0.0001768827,0.000002969367,0.000865579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001251507,"threshold_uncertainty_score":0.004186749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008085039240862039,"score_gpt":0.2337397456890329,"score_spread":0.2256547064481708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}