{"id":"W2329881241","doi":"10.1136/annrheumdis-2015-eular.1628","title":"THU0175 Effects of Baricitinib on Multibiomarker Disease Activity Scores and Their Components in a Phase 2B Study in Moderate-to-Severe Rheumatoid Arthritis Patients","year":2015,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Medicine; Rheumatoid arthritis; Methotrexate; Placebo; Internal medicine; Gastroenterology; TNF inhibitor; Cartilage oligomeric matrix protein; Urology; Osteoarthritis; Pathology; Adalimumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001444167,0.001684437,0.00338347,0.0004973851,0.0004340124,0.001195617,0.000929749,0.001390062,0.00444024],"category_scores_gemma":[0.0008996748,0.0006097572,0.002728364,0.0004866598,0.0007154086,0.000804335,0.0003588096,0.003718453,0.0009691553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007650203,"about_ca_system_score_gemma":0.001300803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001753405,"about_ca_topic_score_gemma":0.004520936,"domain_scores_codex":[0.9996021,0.000146848,0.00002825067,0.00005636747,0.00004728838,0.0001190756],"domain_scores_gemma":[0.9995195,0.00007773277,0.00009606968,0.00003194443,0.00004984794,0.0002250304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8614218,0.02024165,0.004385403,0.001302957,0.003673097,0.0001734081,0.0001149245,0.001400191,0.01941331,0.0002044791,0.005288213,0.08238054],"study_design_scores_gemma":[0.7166182,0.2558297,0.01883805,0.00009647611,0.00211362,0.0002391471,0.0001038034,0.001133785,0.002214163,0.0001220213,0.002623368,0.00006754279],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887276,0.006256519,0.0002409766,0.000658269,0.0003388942,0.0007388218,0.001345291,0.0001415624,0.001552115],"genre_scores_gemma":[0.9876221,0.003885973,0.0007621001,0.0009422179,0.0002632483,0.0008506014,0.002912368,0.00003702148,0.002724392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00444024,"threshold_uncertainty_score":0.01485413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05182186504130101,"score_gpt":0.324490089834696,"score_spread":0.272668224793395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}