{"id":"W2329928107","doi":"10.1097/00007890-201211271-00872","title":"T-Cell Dependency of T-Independent (TI) Antigens: Antibody Response to Blood Group A-Antigen Requires CD4 T-Cells and CD40/CD40L Interaction","year":2012,"lang":"en","type":"article","venue":"Transplantation","topic":"Blood groups and transfusion","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Antigen; Antibody; CD40; B cell; Immunology; Adjuvant; clone (Java method); ABO blood group system; Biology; T cell; Molecular biology; Chemistry; Immune system; Cytotoxic T cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001461428,0.0003972143,0.000199869,0.000232076,0.00009420759,0.0002232283,0.0001901488,0.0002886458,0.002322084],"category_scores_gemma":[0.0001045678,0.0001093234,0.0002506413,0.000101108,0.0002058152,0.0002118753,0.0001852911,0.0008258483,0.000770005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001981113,"about_ca_system_score_gemma":0.0001228334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001941915,"about_ca_topic_score_gemma":0.0002257588,"domain_scores_codex":[0.9998131,0.00003037195,0.00001539635,0.00004603328,0.0000299664,0.00006522991],"domain_scores_gemma":[0.9998053,0.00003271119,0.00005820788,0.00002152732,0.00002280153,0.00005958289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001830801,0.00005674808,0.0002507406,0.00004703339,0.000002614321,0.00003441309,0.000008899034,0.00001691814,0.9985965,0.00004355967,0.00002761619,0.0007318603],"study_design_scores_gemma":[0.00004266908,0.001571056,0.01568397,0.00001624881,0.00002524516,0.0003732094,0.00002682048,0.0004762873,0.9795251,0.00009040706,0.002164178,0.000004944866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937395,0.001582532,0.00142061,0.00006314549,0.00003174782,0.00005731172,0.0004191156,0.00007964112,0.002606379],"genre_scores_gemma":[0.993408,0.0006712691,0.001380915,0.00006342246,0.00003244536,0.00007939884,0.0007638333,0.00002059124,0.00358015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002322084,"threshold_uncertainty_score":0.007768095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396567914723305,"score_gpt":0.2859612052826466,"score_spread":0.2719955261354135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}