{"id":"W2329976634","doi":"10.1158/1538-7445.am2011-4108","title":"Abstract 4108: BH3 only Bcl-2 family member BNIP3 repressed expression of death receptor 5 (DR5) in glioblastoma cells: Implications for regulation of the tumor necrosis factor related apoptosis inducing ligand (TRAIL) cell death pathway","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Apoptosis; Programmed cell death; Cancer research; Tumor necrosis factor alpha; Temozolomide; Glioma; Biology; Small hairpin RNA; Receptor; Chemistry; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005405076,0.0002333999,0.0001522168,0.0001255083,0.0001737324,0.0001633369,0.0001311497,0.0001876911,0.003233881],"category_scores_gemma":[0.00005554886,0.00007111774,0.0001863105,0.0001448766,0.0001309691,0.0001019265,0.0001553875,0.000508243,0.0007983944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003055609,"about_ca_system_score_gemma":0.0002465387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001575104,"about_ca_topic_score_gemma":0.001497355,"domain_scores_codex":[0.999907,0.00001066817,0.000008303217,0.00001382907,0.00002629591,0.00003374433],"domain_scores_gemma":[0.999962,0.000006235818,0.000007379294,0.000004097536,0.000007092518,0.00001330427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001007885,0.0000249232,0.000102448,0.00002478386,0.000001961353,0.0000464997,0.000008990366,0.00001892222,0.9991356,0.00004292202,0.00005677336,0.0004355823],"study_design_scores_gemma":[0.0000323523,0.0002579293,0.007249465,0.000006883251,0.00001207461,0.0002674179,0.00005113366,0.0008923655,0.9885663,0.00005586571,0.002603987,0.000004212854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994042,0.001197157,0.001591735,0.0001756101,0.00006872517,0.00002752258,0.001103275,0.00006170934,0.001732167],"genre_scores_gemma":[0.9913588,0.0004785262,0.001095542,0.0001177416,0.000009207204,0.00004315596,0.002626187,0.00001689199,0.004253925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003233881,"threshold_uncertainty_score":0.01081842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0864611690604593,"score_gpt":0.3317901583564123,"score_spread":0.245328989295953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}