{"id":"W2330101410","doi":"10.1021/ja301680m","title":"How Lipid Unsaturation, Peroxyl Radical Partitioning, and Chromanol Lipophilic Tail Affect the Antioxidant Activity of α-Tocopherol: Direct Visualization via High-Throughput Fluorescence Studies Conducted with Fluorogenic α-Tocopherol Analogues","year":2012,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Free Radicals and Antioxidants","field":"Chemistry","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Universities Space Research Association","keywords":"Chemistry; Tocopherol; Antioxidant; Degree of unsaturation; Fluorescence; Biochemistry; Vitamin E; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004666661,0.0003165717,0.0007572652,0.00001748269,0.0002998635,0.0000718719,0.0004099795,0.000115818,0.00002362851],"category_scores_gemma":[0.0003383948,0.0001680475,0.0003997449,0.0004989154,0.002419156,0.0004279308,0.0001396506,0.0005277352,5.713543e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001796494,"about_ca_system_score_gemma":0.00009808227,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000715604,"about_ca_topic_score_gemma":0.00000641314,"domain_scores_codex":[0.9979414,0.0002024785,0.000472649,0.0002636651,0.0006988152,0.0004209718],"domain_scores_gemma":[0.9973609,0.0003714833,0.001451002,0.0003587761,0.0002855646,0.0001722406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001454229,0.0002625198,0.01179723,0.0001324436,0.0006746012,0.000001424842,0.0006115197,0.000007420613,0.9836903,0.00002903751,0.001321086,0.00132702],"study_design_scores_gemma":[0.000947762,0.0002010319,0.0221255,0.0003174005,0.0003602381,0.0001535982,0.0008331061,0.0003980454,0.9740665,0.0000343816,0.0003027628,0.0002597042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964869,0.001220554,0.0002088873,0.001727853,0.0001016887,0.0001980206,0.0000148708,0.00003158814,0.00000965364],"genre_scores_gemma":[0.9970595,0.001111704,0.0008406394,0.0001507698,0.0007499916,0.00001992801,0.00000303399,0.00003490518,0.00002955773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01032827,"threshold_uncertainty_score":0.8913479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01549588679862782,"score_gpt":0.261425465664874,"score_spread":0.2459295788662462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}