{"id":"W2330101410","doi":"10.1021/ja301680m","title":"How Lipid Unsaturation, Peroxyl Radical Partitioning, and Chromanol Lipophilic Tail Affect the Antioxidant Activity of α-Tocopherol: Direct Visualization via High-Throughput Fluorescence Studies Conducted with Fluorogenic α-Tocopherol Analogues","year":2012,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Free Radicals and Antioxidants","field":"Chemistry","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Universities Space Research Association","keywords":"Chemistry; Tocopherol; Antioxidant; Degree of unsaturation; Fluorescence; Biochemistry; Vitamin E; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002035684,0.0002895838,0.0002676224,0.00008258374,0.00009854823,0.0003024611,0.0001696688,0.0002686237,0.0003471614],"category_scores_gemma":[0.0002539917,0.0001302445,0.0001685767,0.0001447276,0.0001998501,0.0003618699,0.0001409641,0.0005022596,0.0001543751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002715999,"about_ca_system_score_gemma":0.0001838154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008042537,"about_ca_topic_score_gemma":0.0007938194,"domain_scores_codex":[0.9998965,0.00001631987,0.000006454323,0.00003132834,0.00002174602,0.00002771289],"domain_scores_gemma":[0.999886,0.00002990608,0.00003770226,0.00001040518,0.00002176681,0.00001417066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003744326,0.000006644873,0.0000925246,0.00001087365,0.000002815103,0.000008215016,0.00001027361,0.00003698025,0.9992682,0.00001362491,0.000006878674,0.0005054488],"study_design_scores_gemma":[0.000001913015,0.0000335112,0.000471655,7.828105e-7,0.000006465903,0.00001442929,0.000006472505,0.0003030508,0.9989173,0.000008214897,0.000234247,0.000001979679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921805,0.0009419045,0.00615731,0.00007993085,0.0000144855,0.00002921818,0.0002121255,0.0000727796,0.0003117793],"genre_scores_gemma":[0.9927433,0.001174227,0.004929375,0.00004202849,0.00000521453,0.00003071424,0.0001885815,0.00002960053,0.0008570513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008042537,"threshold_uncertainty_score":0.001970649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01549588679862782,"score_gpt":0.261425465664874,"score_spread":0.2459295788662462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}