{"id":"W2330532211","doi":"10.1139/y2012-006","title":"Autoantibodies against cardiac β<sub>1</sub>-adrenoceptor do not affect the low-affinity state β<sub>1</sub>-adrenoceptor-mediated inotropy in rat cardiomyocytes","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Inotrope; Internal medicine; Endocrinology; Agonist; Pindolol; Receptor; Chemistry; Extracellular; Propranolol; Antagonist; Biology; Medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001338245,0.0003160941,0.0002505735,0.0001721938,0.00007664959,0.0001706409,0.000185139,0.0002840047,0.001330357],"category_scores_gemma":[0.0001841398,0.0001433763,0.0002325981,0.00007183183,0.0002089438,0.0002028654,0.0001208136,0.0006439415,0.000326315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00013415,"about_ca_system_score_gemma":0.0001077428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00037846,"about_ca_topic_score_gemma":0.0004721919,"domain_scores_codex":[0.9998633,0.00001770206,0.00001474868,0.00002544226,0.00002064547,0.00005819865],"domain_scores_gemma":[0.9998006,0.00003606631,0.00004491822,0.00002568008,0.00001957347,0.00007311488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003895827,0.00007028784,0.0004453899,0.00002254022,0.000005762627,0.00007333503,0.0000139403,0.00001161717,0.998152,0.00002240563,0.00002370203,0.0007696245],"study_design_scores_gemma":[0.00009164301,0.003616364,0.04933213,0.00001373411,0.00006193163,0.0006695918,0.00008409619,0.000335755,0.9444755,0.00006203561,0.001249442,0.000007727517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981029,0.0008001024,0.0002828202,0.00003954862,0.00002589196,0.000007799262,0.00008966307,0.00001815565,0.0006329659],"genre_scores_gemma":[0.9970776,0.0006536568,0.0003232549,0.0001263578,0.00002794438,0.00002288439,0.0003472318,0.00001122295,0.001409872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001330357,"threshold_uncertainty_score":0.00445044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008524571441567432,"score_gpt":0.233668160537141,"score_spread":0.2251435890955735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}