{"id":"W2330922763","doi":"10.1242/jcs.129668","title":"NCX3 regulates mitochondrial calcium handling through AKAP121-anchored signaling complex and prevents hypoxia-induced cell death","year":2013,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Biology; Cell biology; Mitochondrion; Cytosol; Cytoplasm; Programmed cell death; Inner mitochondrial membrane; Sodium-calcium exchanger; Biochemistry; Apoptosis; Intracellular; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323016,0.0003489123,0.000526246,0.0001623073,0.0004394339,0.0003217119,0.0002965067,0.0004371591,0.001419457],"category_scores_gemma":[0.0001407162,0.0000938946,0.0003781051,0.0001946368,0.0003550161,0.0002711714,0.0002443255,0.0007003873,0.0003004353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004042531,"about_ca_system_score_gemma":0.0004403012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001158287,"about_ca_topic_score_gemma":0.001819143,"domain_scores_codex":[0.9998695,0.00001361968,0.0000156332,0.00002856249,0.00003527024,0.0000373807],"domain_scores_gemma":[0.999922,0.000005788779,0.00001962413,0.000009130159,0.0000136946,0.00002965699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000558795,0.0000741293,0.0003612002,0.0001050798,0.00001377139,0.0001030496,0.00004188829,0.00006155871,0.9958081,0.0001369058,0.0002187069,0.002516833],"study_design_scores_gemma":[0.0001305273,0.0005623411,0.0147897,0.00001981279,0.00005980669,0.000520678,0.0001633435,0.001492209,0.9742718,0.0001911035,0.007783295,0.00001536962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894796,0.0042118,0.003046984,0.0004062403,0.0001602609,0.00006572058,0.0005259069,0.0002559558,0.001847491],"genre_scores_gemma":[0.9925132,0.001573017,0.001614534,0.0001409801,0.00002031665,0.00008855909,0.0009314185,0.00003348059,0.003084478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001419457,"threshold_uncertainty_score":0.004748523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03321795219611407,"score_gpt":0.2746021831214235,"score_spread":0.2413842309253095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}