{"id":"W2330965779","doi":"10.1056/nejmoa1501481","title":"Daclizumab HYP versus Interferon Beta-1a in Relapsing Multiple Sclerosis","year":2015,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":265,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Daclizumab; Medicine; Multiple sclerosis; Monoclonal antibody; Immunology; Pathogenesis; Interferon beta; BETA (programming language); Receptor; IL-2 receptor; Antibody; Internal medicine; Immune system; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002179261,0.0006471429,0.002094834,0.0004799924,0.0002513566,0.000486023,0.0004938627,0.0008921135,0.002166872],"category_scores_gemma":[0.001757037,0.0003022873,0.0009423699,0.00032848,0.0006593412,0.0005706634,0.0003071911,0.0014005,0.0002783232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003968581,"about_ca_system_score_gemma":0.0006227104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002918121,"about_ca_topic_score_gemma":0.0005452998,"domain_scores_codex":[0.998943,0.0006687262,0.00009490707,0.0001102765,0.00008856019,0.00009451164],"domain_scores_gemma":[0.9985232,0.000637054,0.0003472847,0.00007374262,0.00006850435,0.0003501372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9374881,0.005638177,0.00120174,0.0006622954,0.00061873,0.0000650646,0.00006182722,0.0005003685,0.009563969,0.00009576052,0.0002006542,0.04390332],"study_design_scores_gemma":[0.4570862,0.5280815,0.008539905,0.0001048038,0.0008934248,0.0001992844,0.00004482534,0.001040176,0.002788746,0.0001878068,0.001012556,0.00002074988],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919022,0.006558395,0.0002613082,0.0001914842,0.00014231,0.0003593132,0.00008625588,0.00002826333,0.0004705203],"genre_scores_gemma":[0.9959209,0.002100979,0.0005835657,0.0002011182,0.0001842325,0.0004703763,0.0001063985,0.000005685606,0.0004267119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002179261,"threshold_uncertainty_score":0.01152521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2377815217971941,"score_gpt":0.3577021912436646,"score_spread":0.1199206694464705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}