{"id":"W2330965779","doi":"10.1056/nejmoa1501481","title":"Daclizumab HYP versus Interferon Beta-1a in Relapsing Multiple Sclerosis","year":2015,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":265,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Daclizumab; Medicine; Multiple sclerosis; Monoclonal antibody; Immunology; Pathogenesis; Interferon beta; BETA (programming language); Receptor; IL-2 receptor; Antibody; Internal medicine; Immune system; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002395232,0.0002399785,0.000936488,0.000593923,0.00005070063,0.00001613373,0.0002272301,0.0001005085,0.0001255739],"category_scores_gemma":[0.0067191,0.0001576534,0.000112515,0.0004179772,0.0002267452,0.0002043788,0.0001028907,0.0009130994,0.00001565597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004345782,"about_ca_system_score_gemma":0.0003661015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004462367,"about_ca_topic_score_gemma":0.0004690155,"domain_scores_codex":[0.9969379,0.000214246,0.000938695,0.0002230345,0.001243516,0.0004425654],"domain_scores_gemma":[0.997144,0.0008877845,0.0003301843,0.0002866542,0.0005128796,0.0008384719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.06183178,0.0005110066,0.08976271,0.0001581017,0.0006789709,0.000970247,0.01345837,0.0001937183,0.02956234,0.00004356102,0.1332552,0.669574],"study_design_scores_gemma":[0.7148433,0.02520785,0.09871107,0.008070957,0.0005298905,0.0009051724,0.006582747,0.00120231,0.002622068,0.0001928422,0.1406723,0.0004595022],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9602977,0.008222578,0.0004166776,0.02239304,0.002377525,0.0003469293,0.000002911525,0.00002877934,0.005913865],"genre_scores_gemma":[0.9916067,0.002311421,0.001600268,0.0002022017,0.003837365,0.000002775281,0.000006360929,0.00003125833,0.0004016906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6691145,"threshold_uncertainty_score":0.8043876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2377815217971941,"score_gpt":0.3577021912436646,"score_spread":0.1199206694464705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}