{"id":"W2330989831","doi":"10.1213/ane.0000000000001171","title":"The Effects of the Toll-Like Receptor 4 Antagonist, Ibudilast, on Sevoflurane’s Minimum Alveolar Concentration and the Delayed Remifentanil-Induced Increase in the Minimum Alveolar Concentration in Rats","year":2016,"lang":"en","type":"article","venue":"Anesthesia & Analgesia","topic":"Veterinary Pharmacology and Anesthesia","field":"Veterinary","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Minimum alveolar concentration; Sevoflurane; Antagonist; Remifentanil; Anesthesia; Receptor antagonist; Pharmacology; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002115739,0.0006572276,0.0004882318,0.0003684589,0.000171485,0.0002039614,0.0003297806,0.0004344255,0.001584962],"category_scores_gemma":[0.0002819677,0.0003075354,0.0004514515,0.0001146103,0.0004572859,0.0004275408,0.0001752234,0.001260854,0.0003562849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002678669,"about_ca_system_score_gemma":0.0004479252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007395507,"about_ca_topic_score_gemma":0.001219454,"domain_scores_codex":[0.9998533,0.00002181173,0.00001384867,0.00002256148,0.00002649496,0.00006206986],"domain_scores_gemma":[0.9996933,0.00002786928,0.0001122829,0.00002668075,0.0000385416,0.0001014443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01103658,0.001637115,0.0008082006,0.0001438234,0.00003941356,0.0001591611,0.0000740668,0.0001797539,0.9774694,0.0001392325,0.0001522209,0.008160989],"study_design_scores_gemma":[0.0009322784,0.06200624,0.02217258,0.00004650158,0.0001535887,0.0003988415,0.0002099144,0.001244394,0.9109972,0.0001946281,0.001597593,0.00004626656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984037,0.0006481688,0.0002772156,0.0001028124,0.00003354435,0.00002574234,0.0001263793,0.00002835697,0.0003540384],"genre_scores_gemma":[0.9948146,0.001396841,0.001084757,0.0001117753,0.00003079864,0.0001234774,0.0002459861,0.0000100895,0.00218174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001584962,"threshold_uncertainty_score":0.005302191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01434657239532924,"score_gpt":0.2692805203622383,"score_spread":0.254933947966909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}