{"id":"W2330989831","doi":"10.1213/ane.0000000000001171","title":"The Effects of the Toll-Like Receptor 4 Antagonist, Ibudilast, on Sevoflurane’s Minimum Alveolar Concentration and the Delayed Remifentanil-Induced Increase in the Minimum Alveolar Concentration in Rats","year":2016,"lang":"en","type":"article","venue":"Anesthesia & Analgesia","topic":"Veterinary Pharmacology and Anesthesia","field":"Veterinary","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Minimum alveolar concentration; Sevoflurane; Antagonist; Remifentanil; Anesthesia; Receptor antagonist; Pharmacology; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002088134,0.0004909158,0.0005427268,0.00005335995,0.0006602696,0.0001017114,0.0009339543,0.0002807722,0.00003484018],"category_scores_gemma":[0.0001937737,0.0002184515,0.0002332343,0.0004414232,0.0008530351,0.0003248545,0.00006772737,0.0005110819,0.00002833461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001288248,"about_ca_system_score_gemma":0.0001645686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001979575,"about_ca_topic_score_gemma":0.0001102091,"domain_scores_codex":[0.9934452,0.003908489,0.0008515423,0.0005947666,0.0005378131,0.0006622199],"domain_scores_gemma":[0.9951831,0.003325767,0.0004874021,0.0008221157,0.00007975939,0.0001018971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.02921832,0.0009647417,0.0619402,0.0002196246,0.0003649401,0.003214336,0.00825306,0.000009003819,0.8729553,0.01071414,0.006749162,0.005397191],"study_design_scores_gemma":[0.03538247,0.009475726,0.798222,0.002030468,0.001016031,0.009539993,0.004111893,0.002508308,0.1006607,0.001956876,0.03283528,0.002260191],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800418,0.0009077371,0.000004867012,0.0167084,0.0002140955,0.001909766,0.000004979377,0.00003545316,0.0001729287],"genre_scores_gemma":[0.9952467,0.000768881,0.00001199902,0.003416791,0.0001477186,0.0002302616,0.00001355824,0.00004111219,0.0001229483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7722945,"threshold_uncertainty_score":0.8908193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01434657239532924,"score_gpt":0.2692805203622383,"score_spread":0.254933947966909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}