{"id":"W2331147898","doi":"10.1158/1538-7445.am2011-3421","title":"Abstract 3421: Twist1 and clusterin regulate epithelial-mesenchymal transition","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Clusterin; Gene knockdown; Epithelial–mesenchymal transition; Chromatin immunoprecipitation; Transcription factor; Cancer research; Downregulation and upregulation; Biology; Chemistry; Molecular biology; Gene expression; Promoter; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009157343,0.0004681051,0.000291404,0.0003070456,0.0005411539,0.0004181642,0.0001946624,0.0003347851,0.0078588],"category_scores_gemma":[0.00007862428,0.0001706469,0.0003600928,0.0002906614,0.0002410999,0.0002498904,0.0002507845,0.0005958879,0.001660659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006884637,"about_ca_system_score_gemma":0.0004209502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001063712,"about_ca_topic_score_gemma":0.001223389,"domain_scores_codex":[0.9998806,0.00001076233,0.000007559137,0.00003056888,0.00002943694,0.00004116871],"domain_scores_gemma":[0.9999299,0.000005592782,0.00001859292,0.00000283842,0.00001222049,0.00003079887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007511746,0.00004973517,0.0007379478,0.00026027,0.00001229516,0.0001705028,0.0000337206,0.0001316672,0.9930719,0.0004357244,0.001188337,0.003156844],"study_design_scores_gemma":[0.0001122362,0.0005368257,0.03418604,0.00004270422,0.0000599308,0.0008360271,0.0001785608,0.001770323,0.9306447,0.0003694553,0.03123678,0.00002641973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.949208,0.02122543,0.007601782,0.00176472,0.0006490111,0.0001480152,0.007076671,0.00059513,0.01173101],"genre_scores_gemma":[0.9599418,0.005105359,0.002036302,0.0002692559,0.0001282898,0.0001282612,0.004950934,0.0000550689,0.02738474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0078588,"threshold_uncertainty_score":0.02629036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1654977503019681,"score_gpt":0.4191990824005408,"score_spread":0.2537013320985727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}