{"id":"W2331418330","doi":"10.1021/ol201475j","title":"A Remarkably Simple Protocol for the <i>N</i>-Formylation of Amino Acid Esters and Primary Amines","year":2011,"lang":"en","type":"article","venue":"Organic Letters","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Formylation; Chemistry; Primary (astronomy); Simple (philosophy); Protocol (science); Amino acid; Combinatorial chemistry; Organic chemistry; Biochemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008476011,0.00008095244,0.00009893419,0.00001192461,0.00004282191,0.000008140468,0.0001018839,0.00004498374,0.00002990543],"category_scores_gemma":[0.00004232734,0.00005340048,0.00006593332,0.00004730296,0.00006690808,0.000003930445,0.00004814592,0.00002338679,5.484266e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006438822,"about_ca_system_score_gemma":0.00000879954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001240906,"about_ca_topic_score_gemma":0.00000870902,"domain_scores_codex":[0.9995283,0.00001208999,0.0001432928,0.0001538315,0.00005731315,0.0001051762],"domain_scores_gemma":[0.9996614,0.0000210344,0.00008623242,0.000183593,0.00002360268,0.00002413572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006427772,0.00001834144,0.002037371,0.00004237932,0.00004608382,1.269288e-7,0.00004125327,1.470953e-7,0.9937077,0.000003458035,0.001591748,0.002447118],"study_design_scores_gemma":[0.0003557356,0.00005192565,0.003812342,0.000006812539,0.00003938393,0.00000199515,0.00002289342,0.00001429853,0.9883717,0.00001899746,0.007225936,0.00007796477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9805337,0.00003520124,0.005299471,0.0008682068,0.00001645111,0.01304329,0.00001351029,0.000008762113,0.0001813723],"genre_scores_gemma":[0.9906312,0.000006693371,0.0008150589,0.001250544,0.00009291041,0.007125695,0.00002858696,0.00001713669,0.00003214189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0100975,"threshold_uncertainty_score":0.2177608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01494289897177283,"score_gpt":0.230318529922611,"score_spread":0.2153756309508382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}