{"id":"W2331424907","doi":"10.1021/jo302164c","title":"<i>C</i><sup>8</sup>-Heteroaryl-2′-deoxyguanosine Adducts as Conformational Fluorescent Probes in the <i>Nar</i>I Recognition Sequence","year":2012,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge; University of Guelph; University of Toronto","funders":"University of Toronto; Compute Canada; Western Canada Research Grid; Ontario Innovation Trust","keywords":"Chemistry; Deoxyguanosine; Adduct; Fluorescence; Sequence (biology); Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000983478,0.0001911448,0.0001610729,0.00001470778,0.00008618159,0.00003318527,0.0005728259,0.0001499727,0.0003544929],"category_scores_gemma":[0.0002165332,0.0001198578,0.00009689527,0.0001120965,0.0001352826,0.00003580207,0.0001028403,0.0004147284,0.00002881013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004433272,"about_ca_system_score_gemma":0.0001822865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002892526,"about_ca_topic_score_gemma":5.54321e-7,"domain_scores_codex":[0.9986925,0.00008987848,0.0004546183,0.0001088398,0.0003555539,0.0002986116],"domain_scores_gemma":[0.9990473,0.00005169208,0.0003240347,0.0003225365,0.0001554631,0.00009893541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001322302,0.0001473109,0.0003303342,0.00005034952,0.00004132066,0.000004620782,0.0007971167,0.00001984447,0.9941855,0.000002439164,0.003784598,0.0005043276],"study_design_scores_gemma":[0.000643111,0.00006866649,0.0002419329,0.00006856317,0.00005106079,0.002449814,0.001280907,0.00001363483,0.9872239,0.00008276739,0.007710638,0.0001650506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955418,0.001179957,0.0000530451,0.001241359,0.00006769165,0.0000964489,0.00001526016,0.000005458234,0.001798975],"genre_scores_gemma":[0.9970366,0.0006364088,0.0001637794,0.001237433,0.0006893607,0.000003920969,0.00008764834,0.00002083072,0.0001240475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006961654,"threshold_uncertainty_score":0.488766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01456585094038026,"score_gpt":0.2352609991117761,"score_spread":0.2206951481713958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}