{"id":"W2331637821","doi":"10.1093/neuonc/nou208.10","title":"TRANSCRIPTIONAL REGULATION OF OLIGODENDROGLIAL CELL FATE BY DLX HOMEOBOX GENES: POTENTIAL RELEVANCE TO HISTONE H3.3 MUTATIONS IN PEDIATRIC HIGH GRADE GLIOMA","year":2014,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Biology; Homeobox; Chromatin immunoprecipitation; Transcription factor; DLX5; Genetics; Chromatin; ChIP-on-chip; Promoter; Gene; Cell biology; Gene expression; Chromatin remodeling","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000104126,0.0001595864,0.000162037,0.0001996598,0.00007590968,0.0001840245,0.0001263997,0.000149064,0.0006258345],"category_scores_gemma":[0.0001296072,0.00006375626,0.0001258338,0.0002371925,0.0002058829,0.0000734159,0.0001136815,0.0001874148,0.0001149143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000356344,"about_ca_system_score_gemma":0.0001911342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009474371,"about_ca_topic_score_gemma":0.001403675,"domain_scores_codex":[0.9999366,0.000005392737,0.000004192792,0.00001752781,0.00002005482,0.00001630301],"domain_scores_gemma":[0.9999168,0.00002000714,0.00003581551,0.000003383477,0.000007448376,0.00001670965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007206498,0.00004969236,0.04662121,0.0002143581,0.0000261718,0.0008009271,0.0001064815,0.0007376312,0.9417337,0.0001630428,0.0001371272,0.008689029],"study_design_scores_gemma":[0.00003570446,0.0002761704,0.4928934,0.0000248265,0.0000958425,0.002841065,0.0002845114,0.003605688,0.4959869,0.0003270939,0.003614765,0.00001403857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963136,0.001377083,0.001414928,0.00005674295,0.000004038865,0.00001095285,0.0005438681,0.00003492746,0.0002438431],"genre_scores_gemma":[0.9975229,0.0007719963,0.0009820253,0.00003436082,0.000003790796,0.00001107711,0.0004492062,0.000008956948,0.0002157548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009474371,"threshold_uncertainty_score":0.002585471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01154903315694382,"score_gpt":0.2691950856064863,"score_spread":0.2576460524495424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}