{"id":"W2331672726","doi":"10.1177/1947603515571002","title":"Next Generation Mesenchymal Stem Cell (MSC)–Based Cartilage Repair Using Scaffold-Free Tissue Engineered Constructs Generated with Synovial Mesenchymal Stem Cells","year":2015,"lang":"en","type":"article","venue":"Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"Japan Society for the Promotion of Science; Alberta Innovates","keywords":"Mesenchymal stem cell; Stem cell; Scaffold; Cartilage; Medicine; Chondrocyte; Stem cell transplantation for articular cartilage repair; Autologous chondrocyte implantation; Articular cartilage repair; Tissue engineering; Chondrogenesis; Biomedical engineering; Cellular differentiation; Pathology; Articular cartilage; Cell biology; Adult stem cell; Anatomy; Osteoarthritis; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003774861,0.0006655416,0.0008531998,0.0002800386,0.0002165214,0.0001513093,0.0002071019,0.0003741823,0.00009596717],"category_scores_gemma":[0.00001976589,0.000585936,0.0002020919,0.0005542618,0.0001567774,0.0004222182,0.00009384409,0.00025267,0.00009030473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004459378,"about_ca_system_score_gemma":0.0009658557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002403265,"about_ca_topic_score_gemma":0.00008075462,"domain_scores_codex":[0.996448,0.0002111095,0.0006714505,0.0008904028,0.0009089794,0.0008700764],"domain_scores_gemma":[0.9971527,0.0000524049,0.0002401945,0.001155583,0.0005390697,0.0008600816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003978617,0.0001797897,0.0001911063,0.0001067879,0.00003065892,0.001672622,0.0005255089,0.0009114943,0.9932563,0.00009024895,0.0019001,0.0007375173],"study_design_scores_gemma":[0.009578131,0.002839999,0.000002816094,0.0001556528,0.0005744203,0.0002870954,0.000851565,0.008716789,0.9753174,0.000005465782,0.001090437,0.0005802414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993121,0.001207854,0.00067243,0.00008290987,0.001190754,0.001558262,0.0001171502,0.0005764632,0.001473222],"genre_scores_gemma":[0.9871081,0.00000604614,0.008846932,0.0002075864,0.0008104888,0.00006917133,0.0001928953,0.0001434562,0.002615391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01793892,"threshold_uncertainty_score":0.9996592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04549529410953888,"score_gpt":0.2414290653830589,"score_spread":0.19593377127352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}