{"id":"W2331719721","doi":"10.1021/jp209209x","title":"The Influence of Gap Length on Cooperativity and Rate of Association in DNA-Modified Gold Nanoparticle Aggregates","year":2012,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry C","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Linker; Chemistry; Cooperativity; DNA; Duplex (building); Dissociation (chemistry); Crystallography; Base pair; Dynamic light scattering; Nanoparticle; Biophysics; Absorbance; Oligonucleotide; Stereochemistry; Nanotechnology; Biochemistry; Materials science; Organic chemistry; Chromatography; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006039341,0.0002451371,0.0003459337,0.0001461283,0.0001487339,0.0005433402,0.0003242654,0.0002508407,0.0003955586],"category_scores_gemma":[0.001311045,0.0002458153,0.0002219437,0.0001213616,0.0003146548,0.0004480932,0.0002743456,0.0004105177,0.0001510898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003463357,"about_ca_system_score_gemma":0.0001995043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004690972,"about_ca_topic_score_gemma":0.0005947177,"domain_scores_codex":[0.9995776,0.00007570339,0.00003987124,0.0001120696,0.0001299182,0.00006483008],"domain_scores_gemma":[0.9987752,0.0006349693,0.0002194224,0.0001008357,0.00014248,0.0001270516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001295779,0.00002771815,0.001276419,0.00002961319,0.00001480293,0.0000438182,0.0001256285,0.0004067966,0.9966889,0.00006922691,0.00001648233,0.00117095],"study_design_scores_gemma":[0.000009740568,0.0002689266,0.007362348,0.000004855173,0.00002142483,0.00006720998,0.00005373446,0.005460044,0.9863583,0.00005075221,0.0003311697,0.00001148601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999034,0.0002143666,0.0005182213,0.00001364496,0.000004996031,0.000005736079,0.00001711053,0.00001357042,0.0001783364],"genre_scores_gemma":[0.9990041,0.000115222,0.0005693091,0.00001033712,0.000003209324,0.00001371006,0.00003586225,0.000007220876,0.0002410863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006039341,"threshold_uncertainty_score":0.003193915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008838728898755505,"score_gpt":0.2665989806416303,"score_spread":0.2577602517428748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}