{"id":"W2331763687","doi":"10.1371/journal.pone.0060804","title":"DIDS (4,4-Diisothiocyanatostilbenedisulphonic Acid) Induces Apoptotic Cell Death in a Hippocampal Neuronal Cell Line and Is Not Neuroprotective against Ischemic Stress","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Environmental Health Sciences; National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institutes of Health; National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; University of California, San Diego","keywords":"DIDS; Apoptosis; Cell biology; Biology; Neuroprotection; Viability assay; Programmed cell death; Molecular biology; Fragmentation (computing); Chemistry; Biochemistry; Pharmacology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001974074,0.0003836208,0.0004231066,0.0002574057,0.0002401547,0.0003036087,0.0002152528,0.0004094047,0.001311275],"category_scores_gemma":[0.0001629414,0.0001636852,0.0002935337,0.0002847907,0.0003593421,0.0002440694,0.0002184982,0.0005662328,0.0002773722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003619639,"about_ca_system_score_gemma":0.0004160818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009747568,"about_ca_topic_score_gemma":0.001802292,"domain_scores_codex":[0.9998006,0.00002141816,0.00002659109,0.00004903035,0.00005890373,0.00004345543],"domain_scores_gemma":[0.9998759,0.00002278245,0.0000311509,0.00001913636,0.00002622179,0.00002486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002005226,0.00003274387,0.0001579583,0.00008205756,0.00001036286,0.0001155741,0.00001947225,0.00004830723,0.9983411,0.00008864688,0.00005041621,0.0008529341],"study_design_scores_gemma":[0.00002366819,0.0003359062,0.002486646,0.000008108086,0.0000131199,0.0001741179,0.00002654944,0.0002559302,0.995207,0.0000836027,0.001381214,0.000004126387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873421,0.002575601,0.005466011,0.0002409795,0.0001452473,0.00006451384,0.0009142264,0.0001835592,0.003067913],"genre_scores_gemma":[0.9886394,0.001977518,0.003796628,0.00009899449,0.0000229388,0.00009444967,0.001405389,0.00002518736,0.003939485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001311275,"threshold_uncertainty_score":0.004386663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01757783481065982,"score_gpt":0.211291174054884,"score_spread":0.1937133392442242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}