{"id":"W2331883727","doi":"10.1097/fjc.0000000000000252","title":"Inhibition of Myogenic Tone in Rat Cremaster and Cerebral Arteries by SKA-31, an Activator of Endothelial KCa2.3 and KCa3.1 Channels","year":2015,"lang":"en","type":"article","venue":"Journal of Cardiovascular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Cremaster muscle; Tone (literature); Vascular tone; Medicine; Cerebral arteries; Activator (genetics); Cardiology; Internal medicine; Microcirculation; Vasodilation; Art","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005387776,0.000109524,0.0003699934,0.000119327,0.00001685731,0.000007388706,0.00004659481,0.0001333151,0.000009496824],"category_scores_gemma":[0.00004341205,0.00009929515,0.0001720244,0.00006894332,0.0001103293,0.00003332194,0.00004101286,0.00009295479,1.776318e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001690665,"about_ca_system_score_gemma":0.00007157822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006349718,"about_ca_topic_score_gemma":0.000001039312,"domain_scores_codex":[0.9989793,0.0002203777,0.0003564548,0.0001453545,0.0001784218,0.0001201423],"domain_scores_gemma":[0.9993075,0.00001042747,0.0002652805,0.0000905553,0.0002175532,0.0001086958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009922187,0.0000907129,0.0005731004,0.00003220015,0.0004485285,0.000008196253,0.0002827072,0.0007131196,0.9928563,0.000005280948,0.001265886,0.002731756],"study_design_scores_gemma":[0.004730524,0.000965939,0.0003980295,0.00001312623,0.0001588117,0.0002664359,0.0003673535,0.0001360774,0.9734006,0.00004415819,0.01941487,0.0001041055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941583,0.003374092,0.001389859,0.0001036296,0.0007995121,0.0001235582,0.00001473792,0.00000163597,0.00003464536],"genre_scores_gemma":[0.9985704,0.0005798542,0.00009624627,0.00007186253,0.0006134841,0.00000390136,0.00001700281,0.00001128081,0.00003595862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01945573,"threshold_uncertainty_score":0.4049138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01631554552329916,"score_gpt":0.2678191248002246,"score_spread":0.2515035792769254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}