{"id":"W2331943976","doi":"10.1021/op200278q","title":"Efficient Screening and Library Generation in Parallel C–C Coupling Reactions Mediated by Organosilica Silia<i>Cat</i> Palladium Catalysts","year":2011,"lang":"en","type":"article","venue":"Organic Process Research & Development","topic":"Catalytic Cross-Coupling Reactions","field":"Chemistry","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"SiliCycle (Canada)","funders":"Centre National de la Recherche Scientifique","keywords":"Sonogashira coupling; Palladium; Catalysis; Combinatorial chemistry; Coupling (piping); Heck reaction; Coupling reaction; Chemistry; Palladium catalyst; Organic chemistry; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001481943,0.00138714,0.00130462,0.0012508,0.0005379018,0.0009581078,0.001034362,0.0005716686,0.002344697],"category_scores_gemma":[0.001765211,0.0008876032,0.0008502788,0.001209659,0.0004347558,0.0008586265,0.00131476,0.0008206251,0.001651142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004056463,"about_ca_system_score_gemma":0.0008119677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005087895,"about_ca_topic_score_gemma":0.001220933,"domain_scores_codex":[0.9984073,0.0003022627,0.0001130945,0.0004219178,0.0005654268,0.0001899836],"domain_scores_gemma":[0.9991924,0.0002312484,0.00009243361,0.0002199075,0.0001771199,0.00008688835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002017274,0.0001228617,0.0002865796,0.00009374229,0.00003372776,0.0000600444,0.00003303833,0.0008768884,0.9790047,0.0001724546,0.0001926858,0.01892136],"study_design_scores_gemma":[0.00002197591,0.0003467341,0.0003328619,0.000002199111,0.00003354199,0.00008684729,0.000009047028,0.001434657,0.9965414,0.00007115184,0.001108211,0.00001130224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7979213,0.001456311,0.1861096,0.0001590989,0.00008131762,0.001689417,0.002115938,0.003037805,0.007429266],"genre_scores_gemma":[0.7809381,0.002328656,0.2014878,0.0001253822,0.00005285698,0.001618102,0.004842379,0.0005220361,0.008084613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002344697,"threshold_uncertainty_score":0.007843792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04717072941178768,"score_gpt":0.3013033632495363,"score_spread":0.2541326338377486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}