{"id":"W2331953810","doi":"10.1097/00007890-201211271-01105","title":"The IL-1 Receptor Antagonist Anakinra Enhances Survival and Function of Human Islets during Culture: Implications in Clinical Islet Transplantation","year":2012,"lang":"en","type":"article","venue":"Transplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Islet; Anakinra; Transplantation; Beta cell; Medicine; Endocrinology; Internal medicine; Interleukin 1 receptor antagonist; Allotransplantation; Immunology; Receptor antagonist; Receptor; Diabetes mellitus; Antagonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006006002,0.0002969769,0.0003659741,0.0001312254,0.0001232801,0.0005070306,0.0002119981,0.0002241339,0.001137984],"category_scores_gemma":[0.0002778616,0.00009114733,0.0002123983,0.0001495427,0.0002041704,0.0002452483,0.0001818984,0.000909402,0.0003235734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001110099,"about_ca_system_score_gemma":0.0001503694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000118792,"about_ca_topic_score_gemma":0.0002148435,"domain_scores_codex":[0.9997824,0.00009609962,0.00002091895,0.00002662141,0.00004400202,0.0000298934],"domain_scores_gemma":[0.999826,0.00006666961,0.00002734587,0.0000260075,0.00002456161,0.00002953299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001263023,0.0003519953,0.0006060809,0.0001315145,0.000008899611,0.0000924304,0.00006305586,0.0001458626,0.9864365,0.0000657756,0.0001232554,0.01071151],"study_design_scores_gemma":[0.0001903896,0.007119002,0.01275258,0.00006199742,0.00009164407,0.0009404744,0.0001317773,0.0008964036,0.9723344,0.0001646722,0.005303317,0.00001329118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9587334,0.03083105,0.006656972,0.0003991645,0.0001596053,0.0000907475,0.0001757896,0.0001022346,0.002851102],"genre_scores_gemma":[0.9840696,0.009402889,0.004729181,0.000191233,0.00007433347,0.00007586813,0.000277905,0.00002605456,0.00115294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001137984,"threshold_uncertainty_score":0.003806889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02934917386005157,"score_gpt":0.3251927409824906,"score_spread":0.295843567122439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}