{"id":"W2331955450","doi":"10.1038/sj.onc.1203505","title":"The Ets1 proto-oncogene is upregulated by retinoic acid: characterization of a functional retinoic acid response element in the Ets1 promoter","year":2000,"lang":"en","type":"article","venue":"Oncogene","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"Medical Research Council","keywords":"ETS1; Retinoic acid; Biology; Transcription factor; Response element; Molecular biology; Promoter; Cancer research; Genetics; Cell culture; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000178027,0.0003878742,0.0002646127,0.0003591912,0.0002353372,0.0004227828,0.0002755443,0.0003181672,0.001812685],"category_scores_gemma":[0.0002913923,0.0003213336,0.0004152449,0.0001932567,0.0003405813,0.0002841539,0.0003043213,0.0006098034,0.001060875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005628051,"about_ca_system_score_gemma":0.0002956937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086351,"about_ca_topic_score_gemma":0.001367636,"domain_scores_codex":[0.9998279,0.00002382875,0.00001182743,0.00003688579,0.00004332775,0.00005624562],"domain_scores_gemma":[0.9997435,0.0000654839,0.00005646024,0.00003025611,0.00004282478,0.00006140671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001215048,0.000006677255,0.0001892829,0.000013505,0.000001949358,0.00003957492,0.00001457741,0.00004475449,0.9989818,0.0001650564,0.00001471128,0.0004067426],"study_design_scores_gemma":[0.00001511118,0.00004635199,0.00797868,0.000009931904,0.0000131888,0.0004105619,0.0000632274,0.0007510229,0.9880584,0.0001637056,0.002483476,0.000006455624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895182,0.001854369,0.005895632,0.0001993695,0.00002988885,0.00002077997,0.0007634536,0.00009458774,0.001623679],"genre_scores_gemma":[0.9895443,0.0006544109,0.002598321,0.00005162211,0.0000121217,0.00002032584,0.002208724,0.00005114146,0.004859055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001812685,"threshold_uncertainty_score":0.006064057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006285437026813089,"score_gpt":0.2244091231027461,"score_spread":0.218123686075933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}