{"id":"W2331964856","doi":"10.1136/annrheumdis-2014-eular.5589","title":"SAT0408 Long-Term Safety and Tolerability of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Pooled Safety Analysis of Three Phase 3, Randomized, Controlled Trials","year":2014,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Antiplatelet Therapy and Cardiovascular Diseases","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital","funders":"","keywords":"Medicine; Apremilast; Tolerability; Psoriatic arthritis; Placebo; Adverse effect; Randomized controlled trial; Internal medicine; Nausea; Gastroenterology; Surgery; Arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007951599,0.001559747,0.005622193,0.0008349423,0.0004452656,0.001733681,0.0009004003,0.001895046,0.002258132],"category_scores_gemma":[0.006018993,0.0008935346,0.01094367,0.001131511,0.000955051,0.001455482,0.0004899669,0.002597666,0.0004133543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006024945,"about_ca_system_score_gemma":0.0009941184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000471134,"about_ca_topic_score_gemma":0.001281161,"domain_scores_codex":[0.996704,0.001954296,0.0004739538,0.0003633081,0.0003529604,0.0001513877],"domain_scores_gemma":[0.9958549,0.002146251,0.001071879,0.0003254146,0.0003163275,0.000285097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.8402457,0.001312573,0.004764918,0.007293398,0.09147859,0.0001065654,0.00006552831,0.001632836,0.00358379,0.000107549,0.001204302,0.04820423],"study_design_scores_gemma":[0.8025931,0.08114175,0.02346969,0.0004633223,0.0866546,0.0003524253,0.00008479658,0.00160318,0.001440486,0.0003775986,0.00171593,0.0001031975],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8469481,0.1406004,0.003169541,0.001043642,0.0009316193,0.001706123,0.002723613,0.0002952123,0.00258162],"genre_scores_gemma":[0.970943,0.02152555,0.001805988,0.001182151,0.0006230825,0.001095055,0.001982159,0.00003660037,0.0008064279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007951599,"threshold_uncertainty_score":0.04205257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0190196144959197,"score_gpt":0.293338388482158,"score_spread":0.2743187739862383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}