{"id":"W2332217343","doi":"10.1093/neuonc/nov061.77","title":"MB-01 * NOTCH1 PROMOTES MYC MEDULLOBLASTOMA METASTASIS, INITIATION AND MAINTENANCE","year":2015,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medulloblastoma; Cancer research; Flow cytometry; Metastasis; Population; Cell; Downregulation and upregulation; Primary tumor; Cerebrospinal fluid; Western blot; Medicine; Cancer stem cell; Cell culture; Biology; Cancer; Pathology; Oncology; Internal medicine; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000819967,0.0001347276,0.0001536954,0.0002218904,0.0001494044,0.0002658343,0.0001347369,0.0001452709,0.001784419],"category_scores_gemma":[0.00009972365,0.00008304462,0.0001515229,0.0001154712,0.0001328419,0.0001378109,0.000174386,0.0005003879,0.0005774557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003197244,"about_ca_system_score_gemma":0.0002337771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003143513,"about_ca_topic_score_gemma":0.003473964,"domain_scores_codex":[0.9999123,0.00001169569,0.000009078253,0.00001365556,0.00002411715,0.00002919444],"domain_scores_gemma":[0.9999291,0.0000108856,0.000009732938,0.00000888951,0.000008345995,0.00003303411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002257888,0.0001197305,0.0006354505,0.00003002715,0.000003779307,0.00008463333,0.00002938572,0.00005283556,0.9960232,0.0002405073,0.0001817906,0.002372836],"study_design_scores_gemma":[0.00003545704,0.000823335,0.01954065,0.00001180059,0.000015324,0.0004587381,0.000100359,0.001630788,0.9697175,0.00008440088,0.007578154,0.000003506703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951714,0.001012765,0.0008626994,0.00009022592,0.00002339156,0.00002174681,0.0004215945,0.00005996315,0.002336217],"genre_scores_gemma":[0.995883,0.000347646,0.0004901454,0.00003272758,0.000005511367,0.00001637026,0.0004436273,0.00001213175,0.002768942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003143513,"threshold_uncertainty_score":0.006250441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04058908769832843,"score_gpt":0.3121804939516963,"score_spread":0.2715914062533679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}