{"id":"W2332268372","doi":"10.1021/bi301317d","title":"Investigating the Structural Dynamics of α-1,4-Galactosyltransferase C from <i>Neisseria meningitidis</i> by Nuclear Magnetic Resonance Spectroscopy","year":2012,"lang":"en","type":"article","venue":"Biochemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Active site; Galactosyltransferase; Substrate (aquarium); Nuclear magnetic resonance spectroscopy; Conformational change; Neisseria meningitidis; Acceptor; Substrate analog; Stereochemistry; Crystallography; Biophysics; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007064722,0.0001526011,0.00008063907,0.00005842471,0.0001028043,0.0001583225,0.0001616871,0.0001504958,0.0003811553],"category_scores_gemma":[0.0001645008,0.00006929283,0.00009958006,0.00006724552,0.0001263311,0.0001006921,0.00005575658,0.0002687999,0.0000900881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003193771,"about_ca_system_score_gemma":0.0001093166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002413868,"about_ca_topic_score_gemma":0.001999408,"domain_scores_codex":[0.9999759,0.000003693383,0.00000130872,0.000005246773,0.00000718109,0.00000670869],"domain_scores_gemma":[0.9999435,0.00001228499,0.00002014246,0.000004039533,0.000009190827,0.00001081939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006763715,0.00001662846,0.0009828777,0.00001532056,0.000005102247,0.00004102588,0.0000297181,0.0001631758,0.9979285,0.00005284896,0.00002046976,0.0006766106],"study_design_scores_gemma":[0.00001583739,0.0002873899,0.03093315,0.00000887276,0.0000256387,0.0003098418,0.000106947,0.01152411,0.9550369,0.00006385872,0.001673553,0.00001389768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992824,0.00008998975,0.0003883062,0.00001968026,0.000001661253,0.000002606916,0.00003631926,0.000005667504,0.0001733154],"genre_scores_gemma":[0.9983574,0.0001592699,0.000977953,0.00001446275,0.000002281214,0.000004140302,0.0001918313,0.000005941328,0.0002868812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002413868,"threshold_uncertainty_score":0.004799664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006155060081332796,"score_gpt":0.2398337666238456,"score_spread":0.2336787065425128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}